Build robust backtesting systems for trading strategies with proper handling of look-ahead bias, survivorship bias, and transaction costs. Use when developing trading algorithms, validating strategies, or building backtesting infrastructure.

Master Python asyncio, concurrent programming, and async/await patterns for high-performance applications. Use when building async APIs, concurrent systems, or I/O-bound applications requiring non-blocking operations.

Build production Apache Airflow DAGs with best practices for operators, sensors, testing, and deployment. Use when creating data pipelines, orchestrating workflows, or scheduling batch jobs.

Statistical visualization with pandas integration. Use for quick exploration of distributions, relationships, and categorical comparisons with attractive defaults. Best for box plots, violin plots, pair plots, heatmaps. Built on matplotlib. For interactive plots use plotly; for publication styling use scientific-visualization.

Query Reactome REST API for pathway analysis, enrichment, gene-pathway mapping, disease pathways, molecular interactions, expression analysis, for systems biology studies.

Phylogenetic tree toolkit (ETE). Tree manipulation (Newick/NHX), evolutionary event detection, orthology/paralogy, NCBI taxonomy, visualization (PDF/SVG), for phylogenomics.

This skill should be used when users want to run any workload on Hugging Face Jobs infrastructure. Covers UV scripts, Docker-based jobs, hardware selection, cost estimation, authentication with tokens, secrets management, timeout configuration, and result persistence. Designed for general-purpose compute workloads including data processing, inference, experiments, batch jobs, and any Python-based tasks. Should be invoked for tasks involving cloud compute, GPU workloads, or when users mention running jobs on Hugging Face infrastructure without local setup.

Expert-level browser automation, debugging, and performance analysis using Chrome DevTools MCP. Use for interacting with web pages, capturing screenshots, analyzing network traffic, and profiling performance.