Direct REST API access to PubMed. Advanced Boolean/MeSH queries, E-utilities API, batch processing, citation management. For Python workflows, prefer biopython (Bio.Entrez). Use this for direct HTTP/REST work or custom API implementations.

Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target identification.

Presentation toolkit (.pptx). Create/edit slides, layouts, content, speaker notes, comments, for programmatic presentation creation and modification.

Document toolkit (.docx). Create/edit documents, tracked changes, comments, formatting preservation, text extraction, for professional document processing.

Master C#/.NET backend development patterns for building robust APIs, MCP servers, and enterprise applications. Covers async/await, dependency injection, Entity Framework Core, Dapper, configuration, caching, and testing with xUnit. Use when developing .NET backends, reviewing C# code, or designing API architectures.

Automate changelog generation from commits, PRs, and releases following Keep a Changelog format. Use when setting up release workflows, generating release notes, or standardizing commit conventions.

Configure and optimize Nx monorepo workspaces. Use when setting up Nx, configuring project boundaries, optimizing build caching, or implementing affected commands.

Master authentication and authorization patterns including JWT, OAuth2, session management, and RBAC to build secure, scalable access control systems. Use when implementing auth systems, securing APIs, or debugging security issues.

Optimize Apache Spark jobs with partitioning, caching, shuffle optimization, and memory tuning. Use when improving Spark performance, debugging slow jobs, or scaling data processing pipelines.

Build production Apache Airflow DAGs with best practices for operators, sensors, testing, and deployment. Use when creating data pipelines, orchestrating workflows, or scheduling batch jobs.

Configure Istio traffic management including routing, load balancing, circuit breakers, and canary deployments. Use when implementing service mesh traffic policies, progressive delivery, or resilience patterns.

Design durable workflows with Temporal for distributed systems. Covers workflow vs activity separation, saga patterns, state management, and determinism constraints. Use when building long-running processes, distributed transactions, or microservice orchestration.