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fastqc-report-interpreter

Use when analyzing FASTQC quality reports from sequencing data, identifying quality issues in NGS datasets, or troubleshooting sequencing problems. Interprets quality metrics and provides actionable recommendations for RNA-seq, DNA-seq, and ChIP-seq data.

Install with Tessl CLI

npx tessl i github:aipoch/medical-research-skills --skill fastqc-report-interpreter
What are skills?

85

Does it follow best practices?

Validation for skill structure

SKILL.md
Review
Evals

Discovery

89%

Based on the skill's description, can an agent find and select it at the right time? Clear, specific descriptions lead to better discovery.

This is a strong skill description with excellent trigger term coverage and completeness. The 'Use when' clause is well-structured with multiple specific scenarios. The main weakness is that the capabilities could be more concrete - listing specific quality metrics or analysis actions would strengthen specificity.

Suggestions

Add specific concrete actions like 'analyze per-base quality scores, detect adapter contamination, assess GC content, identify overrepresented sequences' to improve specificity

DimensionReasoningScore

Specificity

Names the domain (FASTQC quality reports, NGS datasets) and some actions (interprets quality metrics, provides recommendations), but doesn't list specific concrete actions like 'analyze per-base quality scores, detect adapter contamination, assess GC content distribution'.

2 / 3

Completeness

Explicitly answers both what ('Interprets quality metrics and provides actionable recommendations') and when ('Use when analyzing FASTQC quality reports...identifying quality issues...troubleshooting sequencing problems'). Has clear 'Use when' clause with explicit triggers.

3 / 3

Trigger Term Quality

Excellent coverage of natural terms users would say: 'FASTQC', 'quality reports', 'sequencing data', 'NGS', 'RNA-seq', 'DNA-seq', 'ChIP-seq', 'quality issues', 'sequencing problems'. These are terms bioinformaticians naturally use.

3 / 3

Distinctiveness Conflict Risk

Very clear niche with distinct triggers specific to FASTQC and NGS sequencing analysis. Unlikely to conflict with other skills due to highly specialized domain terminology (FASTQC, RNA-seq, DNA-seq, ChIP-seq).

3 / 3

Total

11

/

12

Passed

Implementation

72%

Reviews the quality of instructions and guidance provided to agents. Good implementation is clear, handles edge cases, and produces reliable results.

This is a well-organized skill with excellent conciseness and structure. The main weaknesses are the reliance on a custom module that may not be available (reducing actionability) and the lack of explicit validation steps for batch operations. The content effectively covers FASTQC interpretation with clear metrics tables and issue diagnosis.

Suggestions

Add validation steps for batch analysis (e.g., 'Verify output file exists and contains expected number of samples before proceeding')

Either provide the FASTQCInterpreter implementation or replace with executable code using standard libraries like parsing HTML/text files directly

Include a feedback loop for handling failed samples in batch processing (e.g., 'If analysis fails: check file format, verify FASTQC completed successfully, retry with verbose logging')

DimensionReasoningScore

Conciseness

The content is lean and efficient, presenting information in tables and code blocks without explaining basic concepts Claude would already know. Every section serves a clear purpose with no padding.

3 / 3

Actionability

Provides concrete code examples and CLI commands, but the code references a custom module (FASTQCInterpreter) that may not exist or be available. The examples are illustrative rather than truly executable without the underlying implementation.

2 / 3

Workflow Clarity

The skill presents clear capabilities and issue diagnosis but lacks explicit validation checkpoints or feedback loops. For batch operations, there's no guidance on verifying results or handling failures during processing.

2 / 3

Progressive Disclosure

Well-structured with a quick start, organized sections for different capabilities, and appropriate reference to external documentation (troubleshooting.md) for detailed platform-specific issues. Navigation is clear and one level deep.

3 / 3

Total

10

/

12

Passed

Validation

100%

Checks the skill against the spec for correct structure and formatting. All validation checks must pass before discovery and implementation can be scored.

Validation11 / 11 Passed

Validation for skill structure

No warnings or errors.

Reviewed

Table of Contents

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