clinpgx-database

Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided dosing decisions.

1.70x

Quality

66%

Does it follow best practices?

Impact

99%

1.70x

Average score across 3 eval scenarios

Securityby

Passed

No known issues

Optimize this skill with Tessl

npx tessl skill review --optimize ./scientific-skills/clinpgx-database/SKILL.md

Evaluation results

100%

10%

Pharmacogenomics Batch Query Tool

Rate limiting and error handling

Criteria

Without context

With context

Correct base URL

100%

Rate limit delay

100%

Request timeout

100%

HTTP 429 handling

100%

Exponential backoff

100%

Retry count

100%

Exception catching

100%

404 handling

100%

Uses requests library

100%

98%

56%

Pharmacogenomics Panel Actionability Report

Gene panel CPIC pair discovery

Criteria

Without context

With context

Correct geneDrugPair endpoint

100%

Gene parameter used

100%

CPIC level filtering

100%

CPIC Level A target

100%

Multi-gene loop

100%

Rate limit delay in loop

100%

83%

ClinPGx base URL

100%

Structured export

100%

Summary report generated

100%

Uses requests library

100%

57%

Patient Medication Safety Review for Antiplatelet Therapy

Clinical decision support workflow

Criteria

Without context

With context

Allele endpoint query

80%

100%

geneDrugPair endpoint

37%

100%

CPIC guideline retrieval

60%

100%

Drug label endpoint

62%

100%

Evidence level check

100%

Phenotype category referenced

100%

Phenoconversion mention

100%

ClinPGx base URL

100%

Rate limit compliance

100%

Population frequency awareness

12%

100%

Structured output report

85%

100%

Repository: K-Dense-AI/claude-scientific-skills
Commit: 71add64

Evaluated: 27 days ago
Agent: Claude Code
Model: Claude Sonnet 4.6

Table of Contents

Pharmacogenomics Batch Query Tool Pharmacogenomics Panel Actionability Report Patient Medication Safety Review for Antiplatelet Therapy

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