cosmic-database

Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.

2.33x

Quality

77%

Does it follow best practices?

Impact

98%

2.33x

Average score across 3 eval scenarios

Securityby

Risky

Do not use without reviewing

Optimize this skill with Tessl

npx tessl skill review --optimize ./scientific-skills/cosmic-database/SKILL.md

Evaluation results

95%

45%

COSMIC Mutation Analysis Script for Cancer Research

Download script usage and mutation data analysis

Criteria

Without context

With context

Correct import path

100%

Uses download_cosmic_file

100%

GRCh38 assembly

100%

Correct mutations file path or shorthand

100%

Uses latest version

100%

Correct file path format

100%

pandas TSV separator

100%

gzip compression param

100%

Gene name column

100%

Primary site column

100%

uv pip install

100%

50%

Cancer Driver Gene Classification Tool

Cancer Gene Census analysis, role classification

Criteria

Without context

With context

Correct import path

100%

Uses download_cosmic_file

100%

gene_census data type OR correct filename

100%

get_common_file_path helper

100%

GRCh38 assembly

100%

Role in Cancer column

100%

oncogene filter value

100%

TSG filter value

100%

na=False in str.contains

100%

latest version in path

100%

72%

Comprehensive COSMIC Data Fetching Pipeline

Multi-datatype download, signatures path, CLI usage

Criteria

Without context

With context

Signatures path no assembly prefix

46%

100%

signatures shorthand

100%

fusion_genes shorthand or path

30%

100%

copy_number shorthand or path

30%

100%

get_common_file_path helper

100%

Correct import path

100%

Uses download_cosmic_file

70%

100%

GRCh38 for genomic data

100%

latest in genomic paths

100%

CLI usage format

40%

100%

Correct genomic path format

100%

Repository: K-Dense-AI/claude-scientific-skills
Commit: 71add64

Evaluated: 27 days ago
Agent: Claude Code
Model: Claude Sonnet 4.6

Table of Contents

COSMIC Mutation Analysis Script for Cancer Research Cancer Driver Gene Classification Tool Comprehensive COSMIC Data Fetching Pipeline

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