gene-database

Query NCBI Gene via E-utilities/Datasets API. Search by symbol/ID, retrieve gene info (RefSeqs, GO, locations, phenotypes), batch lookups, for gene annotation and functional analysis.

1.39x

Quality

70%

Does it follow best practices?

Impact

92%

1.39x

Average score across 3 eval scenarios

Securityby

Passed

No known issues

Optimize this skill with Tessl

npx tessl skill review --optimize ./scientific-skills/gene-database/SKILL.md

Evaluation results

90%

25%

Gene Panel Annotation for Cardiovascular Disease Study

Batch gene annotation

Criteria

Without context

With context

Uses batch script

100%

Organism specified

100%

Output is JSON

100%

gene_annotations.json produced

100%

annotate_genes.py produced

100%

Unresolved symbols flagged

100%

Required fields present

100%

Rate-limit delay

100%

API key parameter

No scratch reimplementation

100%

94%

42%

Insulin Signaling Pathway Gene Report

Multi-API gene discovery workflow

Criteria

Without context

With context

Uses query_gene.py for search

100%

Uses fetch_gene_data.py for detail

100%

Organism specified in search

100%

Pathway field tag used

30%

100%

E-utilities for search step

100%

Datasets API for detail step

100%

pathway_report.json produced

100%

methodology.md produced

100%

Detailed fields retrieved

100%

API key parameter supported

33%

Rate limit respected

100%

93%

12%

Gene Literature Link Builder

Resilient cross-database gene fetching

Criteria

Without context

With context

Exponential backoff

100%

Retry on transient errors

100%

ELink for PubMed links

100%

Batch ESummary used

100%

Chunk size respected

25%

100%

API key parameter

50%

Rate-limit delay

50%

70%

gene_literature.json produced

100%

PubMed IDs in output

100%

Gene summary in output

100%

Repository: K-Dense-AI/claude-scientific-skills
Commit: 71add64

Evaluated: 27 days ago
Agent: Claude Code
Model: Claude Sonnet 4.6

Table of Contents

Gene Panel Annotation for Cardiovascular Disease Study Insulin Signaling Pathway Gene Report Gene Literature Link Builder

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