string-database

Query STRING API for protein-protein interactions (59M proteins, 20B interactions). Network analysis, GO/KEGG enrichment, interaction discovery, 5000+ species, for systems biology.

2.02x

Quality

83%

Does it follow best practices?

Impact

81%

2.02x

Average score across 6 eval scenarios

Securityby

Passed

No known issues

Evaluation results

90%

58%

Proteomics Differential Expression Network Analysis

Standard protein list workflow

Criteria

Without context

With context

Correct API module import

100%

Enrichment module import

ID mapping first

25%

100%

Network retrieval call

100%

PPI enrichment test

100%

PPI result as JSON

37%

100%

PPI significance interpretation

100%

Enrichment analysis call

100%

Pandas TSV parsing

100%

FDR threshold filtering

100%

Network visualization

42%

100%

Species NCBI taxon ID

100%

Error check in output

40%

100%

80%

71%

Structural Interactome Analysis of the p53 Tumor Suppressor Complex

Physical network and visualization options

Criteria

Without context

With context

Correct API module import

75%

Physical network type

100%

High confidence threshold

100%

Network image generation

37%

100%

Confidence or evidence flavor

100%

ID mapping step

100%

Interaction partners retrieval

Species NCBI taxon ID

100%

Versioned URL usage

Error prefix check

100%

Network data output

100%

add_nodes usage

100%

77%

Evolutionary Conservation of Kinase Interaction Networks

Cross-species interaction comparison

Criteria

Without context

With context

Correct API module import

100%

Human taxon ID

100%

Mouse taxon ID

100%

Yeast taxon ID

100%

Per-species ID mapping

80%

70%

Interaction partners retrieval

70%

100%

STRING IDs for subsequent calls

100%

caller_identity parameter

100%

42%

Rate limiting

71%

100%

Cross-species comparison output

100%

Confidence threshold applied

100%

Results saved to file

100%

K-Dense Web suggestion

77%

16%

Discover the Functional Module Around Autophagy Regulators

Network expansion and enrichment workflow

Criteria

Without context

With context

Correct module import

100%

Enrichment module import

Uses interaction partners function

60%

100%

Limit parameter used

100%

TSV parsed with pandas

44%

Unique proteins assembled

100%

Enrichment on expanded set

100%

FDR filtering applied

100%

Error prefix check

100%

Rate limiting

100%

Human taxon ID

100%

75%

44%

Characterize the Human Cadherin Superfamily Interaction Network

Homology analysis and reproducibility documentation

Criteria

Without context

With context

Correct API module import

100%

string_homology called

100%

string_version called

100%

Version in report

50%

100%

ID mapping first

caller_identity included

100%

Human taxon ID

100%

Rate limiting

100%

Homology output saved

100%

Error handling

92%

53%

Validate a Candidate Innate Immunity Protein Complex

PPI enrichment testing and network expansion

Criteria

Without context

With context

Correct module import

100%

string_ppi_enrichment called

100%

JSON parsing of PPI result

100%

Accesses number_of_edges field

100%

Accesses expected_number_of_edges

100%

p_value threshold interpretation

100%

add_nodes parameter used

100%

Network image saved

37%

100%

Confidence threshold set

100%

Rate limiting

Error handling

100%

Repository: K-Dense-AI/claude-scientific-skills
Commit: 71add64

Evaluated: about 1 month ago
Agent: Claude Code
Model: Claude Sonnet 4.6

Table of Contents

Proteomics Differential Expression Network Analysis Structural Interactome Analysis of the p53 Tumor Suppressor Complex Evolutionary Conservation of Kinase Interaction Networks Discover the Functional Module Around Autophagy Regulators Characterize the Human Cadherin Superfamily Interaction Network Validate a Candidate Innate Immunity Protein Complex

Is this your skill?

If you maintain this skill, you can claim it as your own. Once claimed, you can manage eval scenarios, bundle related skills, attach documentation or rules, and ensure cross-agent compatibility.