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blockbuster-therapy-predictor

Predict which early-stage biotechnology platforms (PROTAC, mRNA, gene editing, etc.) have the highest potential to become blockbuster therapies. Analyzes clinical trial progression, patent landscape maturity, and venture capital funding trends to generate investment and R&D prioritization scores. Trigger when: User asks about technology investment potential, platform selection, or therapeutic modality comparison.

82

2.96x
Quality

75%

Does it follow best practices?

Impact

95%

2.96x

Average score across 3 eval scenarios

SecuritybySnyk

Passed

No known issues

Optimize this skill with Tessl

npx tessl skill review --optimize ./scientific-skills/Evidence insights/blockbuster-therapy-predictor/SKILL.md
SKILL.md
Quality
Evals
Security

Evaluation results

90%

65%

Biotech Investment Portfolio Screening

Threshold filtering and JSON report generation

Criteria
Without context
With context

Correct script invocation

50%

100%

Threshold flag used

0%

100%

JSON output flag used

0%

100%

Save flag used

0%

80%

high_potential_report.json exists

100%

100%

JSON structure correct

25%

100%

Rankings contain required fields

25%

100%

Only high-threshold techs included

100%

100%

Strongly Recommended threshold correct

0%

100%

Recommended threshold correct

0%

100%

Watch threshold correct

0%

0%

97%

49%

Nucleic Acid Platform Head-to-Head Analysis

Technology filtering and component score interpretation

Criteria
Without context
With context

Correct tech names

50%

100%

Tech filter applied

30%

100%

Quick mode used

0%

100%

Save flag used

0%

87%

JSON file present

100%

100%

Three platforms in JSON

100%

100%

Formula weights correct

0%

100%

Three component scores listed

100%

100%

Correct script entry point

87%

75%

JSON rankings fields present

0%

100%

No extra platforms

100%

100%

99%

74%

R&D Prioritization Study: Full Technology Landscape

Full analysis execution and scoring methodology

Criteria
Without context
With context

Correct script invocation

100%

87%

JSON output flag

0%

100%

Save flag with correct filename

0%

100%

JSON file present

100%

100%

All 10 platforms in JSON

40%

100%

Market Potential weight

0%

100%

Maturity weight

0%

100%

Momentum weight

0%

100%

Strongly Recommended tier described

0%

100%

Watch tier described

0%

100%

Cautious tier described

0%

100%

Timeline fields used

70%

100%

Repository
aipoch/medical-research-skills
Evaluated
Agent
Claude Code
Model
Claude Sonnet 4.6

Table of Contents

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