CtrlK
BlogDocsLog inGet started
Tessl Logo

ssgsea-immune-infiltration-analysis

Use when estimating immune infiltration from bulk RNA-seq expression matrices with ssGSEA/GSVA, comparing case versus control groups, and generating downstream immune-score visualizations. NOT for single-cell RNA-seq, absolute cell proportion estimation, or clinical decision making.

69

Quality

85%

Does it follow best practices?

Run evals on this skill

Adds up to 20 points to the overall score

View guide

SecuritybySnyk

Passed

No findings from the security scan

SKILL.md
Quality
Evals
Security

Quality

Content

82%Weight 40%Scale 1-5

Reviews the quality of instructions and guidance provided to agents. Good implementation is clear, handles edge cases, and produces reliable results.

A well-structured, highly actionable skill body that leans on tables and executable examples rather than prose, with a clear navigation table to one-level-deep references. Main weaknesses are some environment-sensitive auditing prose and a few navigation entries pointing to files not present in the bundle.

Suggestions

Tighten the 'Validated path note': drop the 'current audited environment' framing and state the validated GSVA/Gaussian baseline as a stable fact, or move environment-specific audit detail into references/cli-guide.md.

Resolve dead navigation links: either add the missing DESCRIPTION file and tests/ directory to the bundle, or remove the DESCRIPTION and tests/run_tests.R / tests/test_skill.R rows from the 'When to Read External Files' table.

Add an explicit validation checkpoint to the Workflow section (e.g., 'Verify output structure against output_manifest.txt and run tests/test_skill.R before reporting success') to lift workflow clarity toward the top anchor for this batch operation.

DimensionReasoningScore

Conciseness

Mostly lean — tight tables for arguments, inputs, outputs, and errors with no padding explaining concepts Claude already knows. Not 5 because the 'Validated path note' carries slightly redundant, environment-sensitive auditing prose ('In the current audited environment, gsva with Gaussian completed successfully...'); not 3 because nearly every section earns its place.

4 / 5

Actionability

Provides a copy-paste-ready Rscript invocation, a complete arguments table with defaults and types, concrete CSV input examples, an explicit output-file table, and test commands. Matches the top anchor of fully executable guidance covering common cases; clearly above the 4 anchor.

5 / 5

Workflow Clarity

Four-step workflow with a schema pre-check (step 1), output review of run_record.txt/output_manifest.txt (step 3), and an error-recovery loop (step 4: 'If execution fails, read references/troubleshooting.md'). Not 5 because there is no explicit labeled 'validate results structure' checkpoint in the main flow (that is deferred to tests); not 3 because verification signals are present rather than absent, so the batch-operation cap does not apply.

4 / 5

Progressive Disclosure

A 'When to Read External Files' table clearly signals each one-level-deep reference (algorithm.md, cli-guide.md, troubleshooting.md, main.R) with purpose, and detail is appropriately split into reference files. Not 5 because the navigation table also references DESCRIPTION and tests/run_tests.R / tests/test_skill.R, which are absent from the bundle (dead links); not 3 because structure and signaling are genuinely good.

4 / 5

Total

17

/

20

Passed

Description

87%Weight 40%Scale 1-5

Based on the skill's description, can an agent find and select it at the right time? Clear, specific descriptions lead to better discovery.

A strong, specific description that explicitly states both capability and trigger conditions, with clear negative boundaries that sharply reduce conflict risk. Keyword coverage is good for this specialized niche though it lacks synonym/extension variations.

DimensionReasoningScore

Specificity

Names the domain and lists several concrete actions — 'estimating immune infiltration', 'comparing case versus control groups', and 'generating downstream immune-score visualizations' — with only minor coverage gaps. Not 5 because the actions are clustered around one pipeline rather than a comprehensive set of distinct operations; not 3 because it clearly goes beyond 1-2 actions.

4 / 5

Completeness

Explicitly answers both what ('estimating... comparing... generating...') and when ('Use when...'), plus concrete negative triggers ('NOT for single-cell...'). Matches the top anchor that requires explicit what AND when with concrete trigger phrases; clearly above the 4 anchor.

5 / 5

Trigger Term Quality

Includes natural domain terms users would say — 'immune infiltration', 'bulk RNA-seq', 'ssGSEA/GSVA', 'case versus control groups' — with good coverage. Not 5 because this niche lacks the synonym/file-extension variations the top anchor expects; not 3 because coverage is solid, not merely 'some relevant keywords'.

4 / 5

Distinctiveness Conflict Risk

Clear niche (ssGSEA/GSVA immune infiltration on bulk RNA-seq) with explicit exclusion boundaries ('NOT for single-cell RNA-seq, absolute cell proportion estimation, or clinical decision making'), giving minimal conflict risk. Matches the top anchor; not 4 because the exclusions make overlap risk negligible.

5 / 5

Total

18

/

20

Passed

Validation

93%

Checks the skill against the spec for correct structure and formatting. All validation checks must pass before discovery and implementation can be scored.

Validation15 / 16 Passed

Validation for skill structure

CriteriaDescriptionResult

frontmatter_unknown_keys

Unknown frontmatter key(s) found; consider removing or moving to metadata

Warning

Total

15

/

16

Passed

Repository
aipoch/medical-research-skills
Reviewed

Table of Contents

Is this your skill?

If you maintain this skill, you can claim it as your own. Once claimed, you can manage eval scenarios, bundle related skills, attach documentation or rules, and ensure cross-agent compatibility.