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esm

Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this skill when working with protein sequences, structures, or function prediction; designing novel proteins; generating protein embeddings; performing inverse folding; or conducting protein engineering tasks. Supports both local model usage and cloud-based Forge API for scalable inference.

63

Quality

76%

Does it follow best practices?

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SecuritybySnyk

High

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tessl review fix ./backend/cli/skills/biology/esm/SKILL.md
SKILL.md
Quality
Evals
Security

Quality

Content

65%Weight 40%Scale 1-5

Reviews the quality of instructions and guidance provided to agents. Good implementation is clear, handles edge cases, and produces reliable results.

A well-structured, actionable skill body with excellent progressive disclosure and concrete code, but it is somewhat verbose and its generation/batch workflows lack explicit validation checkpoints.

Suggestions

Trim padded sections (Best Practices prose, Resources/blog links, repeated install variants) to improve token efficiency.

Add explicit validation/verification checkpoints to generation and Forge batch workflows (e.g., validate generated sequences, verify batch results for errors) to lift workflow clarity.

Make each code example self-contained by defining or noting the 'model' variable and replacing the '<token>' placeholder with a comment on how to supply it.

DimensionReasoningScore

Conciseness

Mostly efficient and code-driven without explaining concepts Claude already knows, but the ~300-line body includes padded sections (Best Practices prose, Resources/blog links, repeated installation variants) that could be trimmed; not 4 because the padding is noticeable, not 2 because it is not heavily padded with concept explanations.

3 / 5

Actionability

Provides multiple concrete, executable code examples with specific imports and model names across the main capabilities; not 5 because several examples assume a 'model' variable defined in earlier sections and use a '<token>' placeholder, so they are not fully self-contained copy-paste ready.

4 / 5

Workflow Clarity

Capability sections are sequenced with 'When to use' and code, and chain-of-thought shows a 3-step refinement, but batch/generation workflows lack explicit validation or verification checkpoints; per the rubric, missing validation in batch operations caps this at 3.

3 / 5

Progressive Disclosure

SKILL.md is a clear overview with well-signaled, one-level-deep references to real files (esm3-api.md, esm-c-api.md, forge-api.md, workflows.md), each annotated with its contents, making navigation easy and content appropriately split.

5 / 5

Total

15

/

20

Passed

Description

87%Weight 40%Scale 1-5

Based on the skill's description, can an agent find and select it at the right time? Clear, specific descriptions lead to better discovery.

A strong description that clearly states capabilities and provides explicit, concrete trigger guidance for when to use the skill. Minor room to sharpen specificity and add common synonyms/file extensions.

DimensionReasoningScore

Specificity

Names the domain and several concrete actions ('designing novel proteins; generating protein embeddings; performing inverse folding'), matching the 'lists several specific actions; minor gaps' anchor; not 5 because 'protein engineering tasks' is somewhat generic, not 3 because there are clearly more than 1-2 concrete actions.

4 / 5

Completeness

Explicitly answers both what ('Comprehensive toolkit for protein language models including ESM3... and ESM C...') and when ('Use this skill when working with protein sequences, structures, or function prediction; designing novel proteins...') with concrete trigger phrases.

5 / 5

Trigger Term Quality

Includes natural user phrases ('protein sequences, structures, function prediction', 'designing novel proteins', 'inverse folding') with good coverage; not 5 because file extensions/synonyms like .fasta or PDB are absent, not 3 because coverage is clearly good rather than partial.

4 / 5

Distinctiveness Conflict Risk

Occupies a clear niche (ESM protein language models) with distinct, domain-specific triggers and minimal overlap risk with other skills.

5 / 5

Total

18

/

20

Passed

Validation

87%

Checks the skill against the spec for correct structure and formatting. All validation checks must pass before discovery and implementation can be scored.

Validation14 / 16 Passed

Validation for skill structure

CriteriaDescriptionResult

metadata_version

'metadata.version' is missing

Warning

frontmatter_unknown_keys

Unknown frontmatter key(s) found; consider removing or moving to metadata

Warning

Total

14

/

16

Passed

Repository
synthetic-sciences/openscience
Reviewed

Table of Contents

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