Generates complete conventional oncology bulk-transcriptome biomarker and hub-gene research designs from a user-provided cancer type and study direction. Always use this skill whenever a user wants to design, plan, or build a tumor bioinformatics study centered on differential expression, prognostic filtering or risk modeling, PPI-based hub-gene prioritization, diagnostic/prognostic evaluation, clinical association, immune infiltration context, methylation context, and optional tissue or cell validation. Covers five study patterns (signature-first prognostic workflow, hub-gene-first biomarker workflow, hybrid signature-to-hub workflow, immune-context biomarker workflow, translational validation workflow) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path...

Design GCP architectures for startups and enterprises. Use when asked to design Google Cloud infrastructure, deploy to GKE or Cloud Run, configure BigQuery pipelines, optimize GCP costs, or migrate to GCP. Covers Cloud Run, GKE, Cloud Functions, Cloud SQL, BigQuery, and cost optimization.

/cs:gc-review <plan> — General Counsel interrogation of contracts, IP, regulatory, term sheets, and employment-law surface. Use when reviewing a term sheet before signing, redlining a customer MSA, or checking IP assignment and regulatory exposure on a new product.

Use when the user asks to capture a full-page screenshot, long screenshot, or complete page capture of a web page. Handles SPA scroll containers, lazy-loaded images, and very tall pages via Chrome DevTools Protocol with zero external dependencies.

Generates complete conventional non-oncology bioinformatics research designs from a user-provided disease context, process-related gene family or biological theme, and validation direction. Use when a study centers on multi-dataset bulk transcriptome integration, DEG analysis, process-gene intersection, enrichment analysis, GSEA, PPI hub-gene prioritization, TF/miRNA regulatory networks, ROC-based biomarker evaluation, and immune infiltration analysis. Covers five study patterns (process-DEG discovery, enrichment/GSEA interpretation, hub-gene prioritization, regulatory-network and immune interpretation, multi-layer public validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

/cs:freeze <decision> <days> — Lock a strategic decision for a cooldown period to prevent impulse reversal. Mirrors gstack's safety primitives for the business layer. Use when an irreversible decision was made under pressure — e.g. a layoff plan or multi-year contract — and deserves a cooling-off lock before execution.

When the user wants to build a free tool for marketing — lead generation, SEO value, or brand awareness. Use when they mention 'engineering as marketing,' 'free tool,' 'calculator,' 'generator,' 'checker,' 'grader,' 'marketing tool,' 'lead gen tool,' 'build something for traffic,' 'interactive tool,' or 'free resource.' Covers idea evaluation, tool design, and launch strategy. For pure SEO content strategy (no tool), use seo-audit or content-strategy instead.

Plans confounder control, variable adjustment logic, and bias mitigation strategies at the protocol stage for clinical, epidemiologic, translational, observational, and biomarker studies. Always use this skill when a user needs to identify major confounders, decide which variables should or should not be adjusted for, compare matching/stratification/weighting approaches, anticipate selection or measurement bias, or pressure-test a study design before execution. Focus on bias sensing, causal structure awareness, variable-role classification, and critical design review rather than generic statistical advice.

/cs:founder-mode <question> — Auto-routes any founder question to the right C-role advisor or to /cs:boardroom for multi-role topics. The single-command entry point. Use when a founder asks any strategic question without knowing which advisor or command fits — e.g. 'runway pressure' routes to the CFO, 'gross retention dropped' routes to the CCO.

Personal leadership development for founders and first-time CEOs. Covers founder archetype identification, delegation frameworks, energy management, CEO calendar audits, leadership style evolution, blind spot identification, imposter syndrome, founder mental health, and succession planning. Use when a founder feels like the bottleneck, struggles to delegate, is burning out, transitioning from IC to executive, managing a board, or when user mentions founder mode, CEO growth, leadership development, delegation, burnout, or imposter syndrome.

When the user wants to optimize any form that is NOT signup/registration — including lead capture forms, contact forms, demo request forms, application forms, survey forms, or checkout forms. Also use when the user mentions "form optimization," "lead form conversions," "form friction," "form fields," "form completion rate," or "contact form." For signup/registration forms, see signup-flow-cro. For popups containing forms, see popup-cro.

Use when the user asks to fix, debug, or make a specific feature/module/area work end-to-end. Triggers: 'make X work', 'fix the Y feature', 'the Z module is broken', 'focus on [area]'. Not for quick single-bug fixes — this is for systematic deep-dive repair across all files and dependencies.

Fix failing or flaky Playwright tests. Use when user says "fix test", "flaky test", "test failing", "debug test", "test broken", "test passes sometimes", or "intermittent failure".

Run financial ratio analysis, DCF valuation, budget variance analysis, and rolling forecasts. Usage: /financial-health <ratios|dcf|budget|forecast> <data.json>

Generates complete comorbidity-oriented shared-biomarker bioinformatics research designs from a user-provided disease pair and validation direction. Use when a study links two clinically related diseases through shared DEGs, enrichment, PPI hub genes, machine-learning feature selection, public diagnostic validation, gene-regulatory networks, immune infiltration, and optional downstream follow-up. Covers five study patterns (shared-DEG discovery, hub-gene prioritization, machine-learning biomarker selection, immune/regulatory interpretation, multi-layer validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

Performs financial ratio analysis, DCF valuation, budget variance analysis, and rolling forecast construction for strategic decision-making. Use when analyzing financial statements, building valuation models, assessing budget variances, or constructing financial projections and forecasts. Also applicable when users mention financial modeling, cash flow analysis, company valuation, financial projections, or spreadsheet analysis.

Router/index for the 2 finance skills bundled in this plugin: financial-analyst (ratio analysis, DCF valuation, budget variance, rolling forecasts) and saas-metrics-coach (ARR/MRR, churn, CAC/LTV, NRR, quick ratio). Use when a finance request doesn't obviously match one skill and you need to pick the right one (e.g., 'analyze these financials', 'how healthy are my SaaS metrics').

Designs retrospective or prospective clinical cohort study protocols for biomedical and clinical research. Always use this skill when the user needs a cohort-based study plan rather than a general study idea, evidence summary, or mechanistic experiment design. Focus on cohort appropriateness, enrollment logic, baseline time-zero definition, follow-up structure, endpoint definition, variable collection, confounding control, and a coherent primary statistical analysis line. Do not invent data availability, follow-up completeness, outcome ascertainment quality, sample size adequacy, or causal interpretability.

Use when adding, retiring, or auditing feature flags. Triggers on "add a flag", "ship behind a flag", "rollout plan", "kill switch", "stale flags", "flag debt", "LaunchDarkly", "GrowthBook", "Statsig", "Unleash", "Flipt", or any progressive-delivery question. Ships flag debt scanner, rollout planner, and kill-switch auditor (all stdlib Python), 4 references on flag taxonomy + provider trade-offs + rollout strategies + lifecycle, plus a /flag-cleanup slash command.

/cs:fda-qsr-audit-prep <scope> — FDA 21 CFR 820 (QSR / QMSR) audit 6-question forcing interrogation. Post-Feb 2026 substantially harmonized with ISO 13485. Use before annual internal QSR audit, pre-FDA-inspection readiness, or Form 483 response.