Use when you need to address review or issue comments on an open GitHub Pull Request using the gh CLI.

Query ChEMBL bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.

Build production-ready GraphQL servers with schema design, resolvers, and subscriptions. Use when building GraphQL APIs with schemas and resolvers. Trigger with phrases like "build GraphQL API", "create GraphQL server", or "setup GraphQL".

Generate client SDKs in multiple languages from OpenAPI specifications. Use when generating client libraries for API consumption. Trigger with phrases like "generate SDK", "create client library", or "build API SDK".

Create distributable Python packages with proper project structure, setup.py/pyproject.toml, and publishing to PyPI. Use when packaging Python libraries, creating CLI tools, or distributing Python code.

Create and manage datasets on Hugging Face Hub. Supports initializing repos, defining configs/system prompts, streaming row updates, and SQL-based dataset querying/transformation. Designed to work alongside HF MCP server for comprehensive dataset workflows.

Execute Juicebox production checklist. Trigger: "juicebox production", "deploy juicebox".

Execute Juicebox enrichment and outreach workflow. Trigger: "juicebox enrich", "candidate enrichment", "talent pool".

Expert patterns for Clerk auth implementation, middleware, organizations, webhooks, and user sync Use when: adding authentication, clerk auth, user authentication, sign in, sign up.

Track and optimize application response times across API endpoints, database queries, and service calls. Use when monitoring performance or identifying bottlenecks. Trigger with phrases like "track response times", "monitor API performance", or "analyze latency".

Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research and patient matching.

Generate gRPC service definitions, stubs, and implementations from Protocol Buffers. Use when creating high-performance gRPC services. Trigger with phrases like "generate gRPC service", "create gRPC API", or "build gRPC server".

Manage Firebase/Firestore operations including CRUD, queries, batch processing, and index/rule guidance. Use when you need to create/update/query Firestore documents, run batch writes, troubleshoot missing indexes, or plan migrations. Trigger with phrases like "firestore operations", "create firestore document", "batch write", "missing index", or "fix firestore query".

Query PubChem via PUG-REST API/PubChemPy (110M+ compounds). Search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics.

Review UI code for Web Interface Guidelines compliance. Use when asked to "review my UI", "check accessibility", "audit design", "review UX", or "check my site against best practices". Fetches latest Vercel guidelines and checks files against all rules.

Build reusable, maintainable UI components following modern design patterns. Use when creating component libraries, implementing design systems, or building scalable frontend architectures. Handles React patterns, composition, prop design, TypeScript, and component best practices.

Automatically updates regression tests based on interval analysis to maintain coverage of key program intervals. Use when code changes affect value ranges, conditionals, or control flow, and existing tests need updating to maintain interval coverage. Analyzes interval information from updated code, identifies coverage gaps, adjusts test inputs and assertions, removes redundant tests, and generates new tests for uncovered intervals. Supports Python, Java, JavaScript, and C/C++ with various test frameworks (pytest, JUnit, Jest, Google Test).

Master defensive Bash programming techniques for production-grade scripts. Use when writing robust shell scripts, CI/CD pipelines, or system utilities requiring fault tolerance and safety.

Access European Nucleotide Archive via API/FTP. Retrieve DNA/RNA sequences, raw reads (FASTQ), genome assemblies by accession, for genomics and bioinformatics pipelines. Supports multiple formats.