Build, deploy, and maintain applications on Hugging Face Spaces — Gradio / Docker / Static SDKs, ZeroGPU and dedicated hardware, model loading, debugging, buckets, inference providers, community grants. Use whenever the user asks to create or host an app on Hugging Face, port code onto ZeroGPU, fix a Space that won't build or run, or otherwise work with `hf spaces …`, `@spaces.GPU`, Space README frontmatter, or the `spaces` Python package.

Reproduce and measure a Mastra Code runtime bug against a real model by driving the built TUI headlessly in tmux while every layer (network, provider stream, run engine, TUI) appends timestamped JSONL. Use when a bug depends on real provider timing, streaming order, or event flow that mocked tests and fixtures may not reproduce — e.g. wrong token rates, flicker, stuck status, ordering races, or "only happens sometimes with a real model".

Review open mastra-ai/mastra GitHub issues, identify direct @mastra/core bugs, and apply the @mastra/core label. Use when auditing issues for core ownership, labeling direct core bugs, or periodically reconciling the @mastra/core issue label.

Review open mastra-ai/mastra GitHub issues, identify direct @mastra/core bugs, and apply the @mastra/core label. Use when auditing issues for core ownership, labeling direct core bugs, or periodically reconciling the @mastra/core issue label.

Translate one, multiple, or all explicitly requested FastGPT i18next namespace JSON files from the completed Simplified Chinese source into every supported target locale, with product-language research and structural validation. Use only when the user explicitly invokes `$i18n-translate` and identifies namespace names, files under `packages/web/i18n/zh-CN/`, or all namespaces; never trigger implicitly for ordinary i18n, copywriting, or documentation work.

Release and recover first-party Composio CLI binaries through Build CLI Binaries, including automatic beta builds, promote-stable dispatches, beta-tag selection, asset and installation verification, and failed release recovery. Use when a contributor asks to build a CLI beta, publish or promote a stable CLI version, choose a release candidate, monitor a CLI release, or diagnose a failed CLI release. Do not use for TypeScript SDK Changesets releases or CLI source implementation.

Read, create, or edit PowerPoint .pptx decks — build slides from an outline, extract slide text/speaker notes, edit shapes/tables/charts, replace images, or export to PDF/images. Use whenever a .pptx (or .ppt) file is an input or output, or the user mentions a deck, slides, or a presentation.

Read, create, or edit Microsoft Word .docx files — extract/summarize text and tables, generate reports/letters/memos with headings, tables, images, TOC and page numbers, do find-and-replace, or apply tracked changes (redlines) and comments. Use whenever the user has a .docx or wants a Word deliverable. Not for PDF, .xlsx, .pptx, or Google Docs.

Builds and troubleshoots TorchDrug 0.2.1 workflows for molecular graphs, property prediction, self-supervised pretraining, molecule generation, retrosynthesis, protein representation learning, and knowledge graph reasoning. Use when code imports torchdrug or needs its datasets, models, tasks, or Engine.

Calculates sample sizes and statistical power for study planning. Applies when someone asks "how many subjects/samples/replicates do I need", wants an a priori power analysis, a minimum detectable effect (MDE), a power curve, or needs to justify a sample size for a grant, IRB protocol, or pre-registration. Covers closed-form power for t-tests, ANOVA, proportions, correlations, chi-square, and regression, plus simulation-based (Monte Carlo) power for complex designs — logistic/Poisson regression, mixed models, cluster-randomized trials, survival, and interactions. Also handles requests that only mention an effect size, alpha, or "80% power" without saying "power analysis" explicitly. For laying out the study (randomization, blocking, factorial/DOE, crossover, sequential designs) use experimental-design; for analyzing data already collected and reporting it use statistical-analysis.

Guided statistical analysis for research data - test selection, assumption checking, effect sizes, power analysis, Bayesian alternatives, and APA-formatted reporting. Use whenever a user wants to compare groups, test a hypothesis, analyze experimental or survey data, check statistical assumptions, compute required sample sizes, or write up results - even if they never name a specific test. Covers t-tests, ANOVA, chi-square, correlation, regression, non-parametric and Bayesian methods. For low-level model APIs, see the statsmodels and pymc skills.

Builds, simulates, transpiles, and executes quantum circuits with Qiskit and IBM Quantum Runtime. Use for Qiskit 2.x circuits and operators, V2 Sampler or Estimator primitives, target-aware transpilation, local or noisy simulation, IBM QPU execution, Runtime sessions or batches, error mitigation, and Qiskit ecosystem packages.

Builds with and operates Pi, the minimal terminal coding harness. Use for installing Pi, configuring providers/models/settings/environment variables, creating Pi skills/extensions/packages/themes/prompt templates, embedding Pi through the SDK, integrating over RPC or JSON event streams, parsing sessions, running local models through the llama.cpp router, developing custom Pi providers and TUI components, or using ecosystem packages such as pi-subagents (delegation/orchestration), pi-mcp-adapter (MCP servers), pi-interview (interactive forms), and pi-web-access (web search, fetching, video understanding).

Performs pathway and gene-set enrichment analysis on gene lists or ranked gene data and interprets the results. Used when the user has a set of genes (differentially expressed genes from PyDESeq2/Scanpy, CRISPR-screen hits, cluster marker genes, proteomics hits) and wants to know which biological pathways, GO terms, or gene sets are over-represented or enriched. Covers over-representation analysis (ORA / Enrichr / Fisher / hypergeometric), ranked Gene Set Enrichment Analysis (GSEA / preranked), single-sample scoring (ssGSEA/GSVA), and functional profiling via gseapy, g:Profiler, Enrichr libraries, MSigDB, GO, KEGG, Reactome, and WikiPathways — plus gene-ID mapping, choosing the right background universe, multiple-testing correction, redundancy reduction, dotplots/enrichment maps, and publication-ready tables. Use this for "pathway analysis", "enrichment analysis", "GO enrichment", "KEGG/Reactome pathways", "GSEA", "over-representation", "functional annotation", or "what pathways are my genes in".

Searches 18 scholarly APIs for papers, preprints, citations, open-access full text, repository records, and journal OA status, and returns results with reproducible provenance. Covers PubMed, PMC, Europe PMC, bioRxiv, medRxiv, arXiv, OpenAlex, Crossref, Semantic Scholar, CORE, Unpaywall, OpenCitations, PubTator3, Zenodo, Figshare, ROR, BioStudies, and DOAJ. Use when searching for papers, citations, DOI/PMID/arXiv lookups, abstracts, full text, open-access PDFs, preprints, citation graphs, author publications, biomedical entity annotations, deposited records (Zenodo, Figshare, BioStudies), institution ROR IDs, or any scholarly literature query. Triggers on mentions of any supported database or requests like "find papers on X", "look up this DOI", "who cites this paper", or "get me the PDF".

Local document and PDF parsing that returns spatial text with bounding boxes. Use for extracting text from PDFs, DOCX, Office files, and images; running OCR on scans; producing layout-preserved JSON for RAG; batch-ingesting folders of papers; or rendering pages to PNG for multimodal agents. Distinguishing capabilities are spatial text boxes, Markdown, page raster output, and local parsing with optional custom HTTP OCR.

Predicts protein-small-molecule binding poses with DiffDock and DiffDock-L from PDB or sequence plus SMILES/SDF/MOL2. Covers batch docking, pose triage, confidence interpretation, and validation. Use for molecular docking and virtual-screening pose generation, not binding-affinity prediction.

Operates Fictiv (app.fictiv.com), the on-demand manufacturing platform, end to end in the user's browser. Covers uploading CAD parts, configuring process, material, finish, threads, tolerances and inspections, getting instant or manual quotes, reading and fixing DFM feedback, choosing lead time and region, checking out and paying (card or PO), tracking orders, reordering, and troubleshooting. Applies when the user mentions Fictiv, wants a part CNC machined, 3D printed, sheet-metal fabricated, urethane cast, injection or compression molded, or die cast through an online service, asks to "get a quote" or "order parts" for a STEP/SLDPRT/STL file, wants to check a Fictiv quote or order status, or has a problem with a Fictiv upload, DFM warning, price or checkout. Also applies when the user wants custom parts manufactured and has a Fictiv account, even if Fictiv is not named.

Estimates intracellular metabolic fluxes from steady-state carbon-13 isotope-tracing measurements using validated atom maps, mfapy isotope simulation, constrained multistart fitting, and flux-profile diagnostics. Use for 13C-MFA, carbon tracing, mass isotopomer distributions (MDVs/MIDs), positional isotopomers, parallel tracer experiments, and determining whether labeling data constrain a pathway flux. Distinguishes measured-label inference from COBRA flux balance analysis and flags experiments requiring nonstationary MFA.

Add a third-party MCP server (Linear, Notion, GitHub, ...) to the PostHog MCP store catalog. Use when asked to "add X to the MCP store", expand the MCP server marketplace, or fix a broken catalog entry. Covers finding the vendor's remote MCP endpoint, probing it (handshake, OAuth discovery, DCR), authoring the catalog entry in products/mcp_store/backend/catalog.py, verification tiers, and the operator handoff for servers without Dynamic Client Registration.