Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.

Clinical and physiological imaging analysis. Diffusion MRI ADC maps, micro-CT bone morphometry, hemodynamic parameter analysis, circadian rhythm cosinor analysis, ciliary beat frequency (FFT), and tissue deformation optical flow. For DICOM file handling use pydicom; for biosignals use neurokit2.

Computational cancer genomics workflows. Somatic mutation detection and annotation, structural variation characterization, copy number analysis, tumor purity/ploidy estimation, NMF metagene extraction, and DNA damage response network analysis. For cancer mutation databases use cosmic-database; for variant clinical significance use clinvar-database.

Academic paper search via Google Scholar using Serper API

Use when Python environment setup is needed for data visualization or conda installation is required

数学建模竞赛最终验证和验收阶段，支持 Typst 和 LaTeX 双引擎。用于论文写完后检查章节数量、标题顺序、图表引用、数值一致性、占位符、内部文件泄露、参考文献、代码可复现性、编译和提交就绪状态。

Cuts GitHub API calls by separating lightweight list scanning from full hydration

Teaches agents to reply to PR review comment threads after fixing issues, making resolutions traceable

Protocol for sending queries, delegating tasks, and sharing context between independent Squad instances across different repositories

How to review PRs for security — credentials, injection, workflow permissions, supply chain, git operation safety

Defensive CI/CD patterns: semver validation, token checks, retry logic, draft detection — earned from v0.8.22

How to review PRs for architectural quality — module boundaries, dependency direction, export surface, pattern consistency

Use acpx as a headless ACP CLI for agent-to-agent communication, including prompt/exec/sessions workflows, session scoping, queueing, permissions, output formats, system-prompt overrides, and multi-agent flows authored with defineFlow/decision/decisionEdge.

AIOX Master Orchestrator & Framework Developer (Orion). Use when you need comprehensive expertise across all domains, framework component creation/modification, workflow orchest...

This skill should be used when the user asks to "debug this", "fix this error", "investigate this bug", "troubleshoot this issue", "find the problem", "something is broken", "this isn't working", "why is this failing", or reports errors/exceptions/bugs. Provides systematic debugging workflow and common error patterns.

Hunting skill for rce vulnerabilities. Built from 67 public bug bounty reports. Use when hunting rce on any target.

Hunting skill for misc vulnerabilities. Built from 225 public bug bounty reports. Use when hunting misc on any target.

Use Iconify Solar Duotone Bold icon style.

Promotes legacy views to modern UI.Widget classes, hooks up performUpdate() rendering, and exports default views.

Reproduce and investigate flakiness in a test.