Full-stack backend architecture and frontend-backend integration guide. TRIGGER when: building a full-stack app, creating REST API with frontend, scaffolding backend service, building todo app, building CRUD app, building real-time app, building chat app, Express + React, Next.js API, Node.js backend, Python backend, Go backend, designing service layers, implementing error handling, managing config/auth, setting up API clients, implementing auth flows, handling file uploads, adding real-time features (SSE/WebSocket), hardening for production. DO NOT TRIGGER when: pure frontend UI work, pure CSS/styling, database schema only.