boltz
Structure prediction for protein, nucleic-acid, and small-molecule complexes with Boltz-2 (Passaro & Wohlwend et al. 2025, github.com/jwohlwend/boltz). Reach for this skill to validate designed binders against a target, to co-fold a protein with a SMILES or CCD ligand, or to get an open-source AlphaFold3 alternative with optional binding-affinity prediction.
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Low-risk findings worth noting
W012: Unverifiable external dependency detected (runtime URL that controls agent).
What this means
The skill fetches instructions or code from an external URL at runtime, and the fetched content directly controls the agent’s prompts or executes code. This dynamic dependency allows the external source to modify the agent’s behavior without any changes to the skill itself.
Why it was flagged
The ColabFold MSA server (`api.colabfold.com`) is queried at runtime via `--use_msa_server` to supply remote sequence alignments required for execution, constituting a common unofficial operational dependency.
- Repository
- aipoch/open-science
- Commit
bf35648
- Audited
- Security analysis
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