ligandmpnn
Inverse-fold a backbone with ligand, nucleic-acid, and metal context using LigandMPNN (Dauparas et al. 2023, github.com/dauparas/LigandMPNN). Reach for this skill to redesign the residues lining a binding pocket around a bound small molecule or cofactor, to design metal-coordinating sites where the geometry must be respected, or to get threaded designed-sequence PDBs out of any MPNN run.
75
94%
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Low-risk findings worth noting
W012: Unverifiable external dependency detected (runtime URL that controls agent).
What this means
The skill fetches instructions or code from an external URL at runtime, and the fetched content directly controls the agent’s prompts or executes code. This dynamic dependency allows the external source to modify the agent’s behavior without any changes to the skill itself.
Why it was flagged
The skill instructs cloning the repository https://github.com/dauparas/LigandMPNN.git and running model parameter download scripts to obtain executable code and behavior-selecting configuration during setup, constituting a common/reputable unofficial operational dependency.
- Repository
- aipoch/open-science
- Commit
bf35648
- Audited
- Security analysis
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