Inverse-fold a protein backbone (PDB structure) into amino-acid sequence with ProteinMPNN (Dauparas et al. 2022, github.com/dauparas/ProteinMPNN). Reach for this skill to run sequence design on RFdiffusion backbones, to redesign one chain of a PDB while holding interface residues fixed, or to generate a temperature-swept set of sequences for downstream folding.
72
91%
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Low-risk findings worth noting
The skill fetches instructions or code from an external URL at runtime, and the fetched content directly controls the agent’s prompts or executes code. This dynamic dependency allows the external source to modify the agent’s behavior without any changes to the skill itself.
The skill instructs cloning the repository from `https://github.com/dauparas/ProteinMPNN.git` at runtime, which is a common/reputable unofficial publisher source (third-party academic/lab project) providing operational code and weights, resulting in a medium severity tier.
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