fair-esm2
Use ESM2 protein language models for embeddings, mutation scoring, remote homology, or representation analysis. Use when a task needs protein embeddings, zero-shot variant scores, clustering, or sequence-function triage.
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tessl review fix ./skills/fair-esm2/SKILL.mdFair ESM2
Use this skill for ESM2-style protein language model analysis.
Workflow:
- Normalize proteins into FASTA with stable identifiers and mutation notation.
- Verify the local package, checkpoint, endpoint, or notebook route before execution.
- Save embeddings, variant-score tables, clustering plots, model version, command, and runtime logs.
- Compare model-derived rankings against UniProt, structures, conservation, assays, or literature.
- Mark sequence regions with poor coverage, disorder, low homology, or domain-boundary ambiguity.
Use ESM2 outputs as features or hypotheses unless a source-backed validation step supports the conclusion.
- Repository
- companion-inc/feynman
- Commit
95c51d9
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- First committed
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