Vibe-Skills

Master discrete mathematics, logic, formal proofs, and computational thinking. Build the mathematical foundation for all computer science.

Create analytical charts and plots from existing data. Use for exploratory or reporting visuals such as bars, lines, scatters, and dashboards; not for publication-grade scientific figures or AI-generated schematics.

Create a concise plan. Use when a user explicitly asks for a plan related to a coding task.

Discover codebase patterns, conventions, and unwritten rules before making changes. Use when implementing features, fixing bugs, or refactoring code.

This skill should be used when the user asks to "understand context", "explain context windows", "design agent architecture", "debug context issues", "optimize context usage", or discusses context components, attention mechanics, progressive disclosure, or context budgeting. Provides foundational understanding of context engineering for AI agent systems.

Assists in writing high-quality content by conducting research, adding citations, improving hooks, iterating on outlines, and providing real-time feedback on each section. Transforms your writing process from solo effort to collaborative partnership.

Ensure thorough validation, error recovery, and transparent reasoning in research tasks with multiple tool calls

Git提交与调试反思报告生成技能。用于分析开发过程中的错误、调试步骤和解决方案,生成结构化的中文反思报告,并创建包含报告引用的Git提交。显式请求词:反思提交、智能提交、生成调试报告、commit with reflection。

Personalized coding tutorials that build on your existing knowledge and use your actual codebase for examples. Creates a persistent learning trail that compounds over time using the power of AI, spaced repetition and quizes.

Default code-quality route for broad code review, PR review, maintainability, correctness, and regression-risk checks. Do not use as the primary route for dedicated OWASP/security audits, review-feedback handling, completion verification, AI-code cleanup, or TDD/test-first work.

Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided dosing decisions.

Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research and patient matching.

Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient documentation (SOAP, H&P, discharge summaries). Full support with templates, regulatory compliance (HIPAA, FDA, ICH-GCP), and validation tools.

Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). Supports GRADE evidence grading, statistical analysis (hazard ratios, survival curves, waterfall plots), biomarker integration, and regulatory compliance. Outputs publication-ready LaTeX/PDF format optimized for drug development, clinical research, and evidence synthesis.

Claude Skills meta-skill: extract domain material (docs/APIs/code/specs) into a reusable Skill (SKILL.md + references/scripts/assets), and refactor existing Skills for clarity, activation reliability, and quality gates.

Comprehensive citation management for academic research. Resolve bibliographic identifiers, extract accurate metadata, validate citations, deduplicate references, and generate properly formatted BibTeX entries. This skill should be used when you need to verify citation information, convert DOIs/PMIDs/arXiv IDs to BibTeX, or ensure reference accuracy in scientific writing.

Query ChEMBL bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.

Codex-compatible cancel command for Ralph loop state, preserving the original command name.

You MUST use this before any creative work - creating features, building components, adding functionality, or modifying behavior. Explores user intent, requirements and design before implementation.

Primary retained Python toolkit for molecular biology sequence work. Preferred for sequence manipulation, FASTA/FASTQ/GenBank parsing, Bio.Entrez, BLAST workflows, alignments, structures, and phylogenetics. For biological database evidence lookup, use bio-database-evidence. For single-cell workflows use scanpy. For direct literature REST API, use pubmed-database.

Unified biological database evidence owner. Use for gene annotation, variant clinical significance, cancer mutation evidence, GWAS trait associations, pathway mapping, target-disease evidence, protein structures, protein interaction networks, reference single-cell census queries, and cross-database biological ID mapping. Do not use for full single-cell analysis, bulk RNA-seq differential expression, BAM/VCF processing, protein embedding models, metabolic flux modeling, genomic interval ML, or flow-cytometry file parsing.

Full-stack software development agent for design, implementation, testing, and deployment. Use when the user explicitly asks for end-to-end project creation, feature development, bug fixing, or code refactoring.

Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical data including celestial coordinates, physical units, FITS files, cosmological calculations, time systems, tables, world coordinate systems (WCS), and astronomical data analysis. Use when tasks involve coordinate transformations, unit conversions, FITS file manipulation, cosmological distance calculations, time scale conversions, or astronomical data processing.

Implement proven backend architecture patterns including Clean Architecture, Hexagonal Architecture, and Domain-Driven Design. Use when architecting complex backend systems or refactoring existing applications for better maintainability.

Access real-time and historical stock market data, forex rates, cryptocurrency prices, commodities, economic indicators, and 50+ technical indicators via the Alpha Vantage API. Use when fetching stock prices (OHLCV), company fundamentals (income statement, balance sheet, cash flow), earnings, options data, market news/sentiment, insider transactions, GDP, CPI, treasury yields, gold/silver/oil prices, Bitcoin/crypto prices, forex exchange rates, or calculating technical indicators (SMA, EMA, MACD, RSI, Bollinger Bands). Requires a free API key from alphavantage.co.