Use when needing clinical significance, pathogenicity classifications (e.g., Pathogenic, Benign, VUS), clinical evidence rationales, or finding "hard positive" benchmark controls for human genomic variants.
63
75%
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Low
Low-risk findings worth noting
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tessl review fix ./skills/clinvar_database/SKILL.mdLow
Low-risk findings.
1 low severity finding. Worth noting, but not necessarily harmful.
The skill exposes the agent to untrusted, user-generated content from public third-party sources, creating a risk of indirect prompt injection. This includes browsing arbitrary URLs, reading social media posts or forum comments, and analyzing content from unknown websites.
The required workflow for `evidence` (via `uv run scripts/clinvar_api.py evidence`) fetches outsider-authored ClinVar submissions from NCBI at runtime and extracts their free-text `Comment` nodes (`comment.text`) into JSON, which becomes LLM-readable context if the agent later ingests that output.
0b42509
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