detecting-pv-signals
Computes disproportionality signals — PRR, ROR, EBGM, and IC (BCPNN) — over FAERS / OpenFDA drug-event data to flag potential safety signals. Use when the user wants to mine spontaneous-report data for drug-reaction associations, build a 2x2 contingency table, compute a Proportional Reporting Ratio or Reporting Odds Ratio, run Empirical Bayes (EBGM/EB05) or Information Component shrinkage, or screen a drug for over-reported reactions. Trigger keywords: disproportionality, signal detection, PRR, ROR, EBGM, EB05, IC, BCPNN, MGPS, 2x2 table, signal of disproportionate reporting, SDR, OpenFDA, FAERS. Pairs adjacent to OpenMed: aggregate de-identified, coded cases (from reporting-adverse-events) then query the public OpenFDA /drug/event count API to build the contingency table. Reaction terms are MedDRA PTs (licensed, user-supplied).
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