Analyze CRISPR-Cas9 genetic screens — MAGeCK gene-level scores, sgRNA count QC, replicate correlation, hit prioritization, and pathway GSEA on screen output. Use for genome-wide essentiality screens, synthetic-lethality discovery, dropout vs positive-selection screen analysis, target identification, and resistance-screen interpretation. Includes screen-QC and statistical thresholds.
85%
Does it follow best practices?
Run evals on this skill
Adds up to 20 points to the overall score
Low
Low-risk findings worth noting
The canonical home for this skill is tooluniverse-crispr-screen-analysis in mims-harvard/ToolUniverse
The skill exposes the agent to untrusted, user-generated content from public third-party sources, creating a risk of indirect prompt injection. This includes browsing arbitrary URLs, reading social media posts or forum comments, and analyzing content from unknown websites.
The required workflow uses PubMed to search for literature articles based on query terms, which constitutes reading external search results containing free text.
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