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tooluniverse-data-integration-analysis

Integrate computed statistical results (DEGs, GWAS hits, associations) with biological context from ToolUniverse databases (UniProt, GO, Reactome, ClinVar, OpenTargets). Use for adding gene function/pathway/disease annotations to a result list, building biological narrative around statistical findings, and going beyond p-values to mechanism.

64

Quality

75%

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tessl review fix ./plugin/skills/tooluniverse-data-integration-analysis/SKILL.md
SKILL.md
Quality
Evals
Security

Quality

Content

50%

Reviews the quality of instructions and guidance provided to agents. Good implementation is clear, handles edge cases, and produces reliable results.

The body is well-structured and domain-rich with concrete query strings and report templates, but it teaches concepts Claude already knows, lacks runnable code, and is monolithic with no progressive disclosure or bundle references. It is competent but improvable across all dimensions.

Suggestions

Trim the conceptual exposition in Step 3 (DAG confounders/mediators/colliders, Mendelian randomization basics) to terse reminders, since Claude already knows these, and keep only the skill-specific application guidance.

Add at least one copy-paste runnable Python example showing the retrieve-then-analyze pattern (e.g., calling find_tools, loading results into pandas, and computing an annotation table) to satisfy the 'COMPUTE, DON'T DESCRIBE' directive.

Add explicit workflow checkpoints for the multi-database querying (e.g., 'if a source returns no hits, retry with broader terms before dropping it') and consider moving the evidence-grading and report-template tables into a single reference file to enable progressive disclosure.

DimensionReasoningScore

Conciseness

Mostly efficient (mapping tables, concrete find_tools queries, report templates) but spends substantial prose explaining causal-inference concepts Claude already knows (DAG confounders/mediators/colliders, Mendelian randomization logic), so it is not fully lean; not a 1 because the tables and tool queries earn their place.

2 / 3

Actionability

Provides concrete tool-discovery query strings (e.g. `find_tools("gene enrichment pathway analysis")`) and reusable table/report templates, but no copy-paste executable code despite the "COMPUTE, DON'T DESCRIBE" directive; not a 3 because there are no runnable examples, and not a 1 because guidance is specific rather than abstract.

2 / 3

Workflow Clarity

Steps are clearly sequenced (Step 1 through Step 5) and Step 4 adds a falsification mindset, but there are no explicit workflow-execution validation checkpoints or error-recovery feedback loops for the batch multi-database querying; not a 1 because the sequence is explicit, but the missing checkpoints cap it at 2 per the batch-operations guideline.

2 / 3

Progressive Disclosure

Content is well-sectioned into headers/tables, but it is a monolithic ~130-line inline body with no bundle files or one-level-deep references, and the evidence-grading/causal-reasoning material arguably could be split out; the under-50-line simple-skill exception does not apply, so it does not reach a 3.

2 / 3

Total

8

/

12

Passed

Description

100%

Based on the skill's description, can an agent find and select it at the right time? Clear, specific descriptions lead to better discovery.

The description is specific, third-person, and clearly pairs what the skill does with an explicit 'Use for' trigger clause and distinct domain terminology. It is a strong, low-conflict description.

DimensionReasoningScore

Specificity

Lists multiple concrete actions in third person ("Integrate computed statistical results (DEGs, GWAS hits, associations) with biological context", "adding gene function/pathway/disease annotations", "building biological narrative", "going beyond p-values to mechanism"), matching the anchor for several specific concrete actions rather than a vague domain-only statement.

3 / 3

Completeness

Explicitly states what it does (integrate statistical results with biological context from named databases) and when to use it via the "Use for ..." trigger clause, satisfying both what and when rather than leaving when implied (which would cap it at 2).

3 / 3

Trigger Term Quality

Covers natural domain terms a bioinformatics user would actually say ("DEGs", "GWAS hits", "associations", "p-values", "gene function", "pathway", "disease", "mechanism"); it is not a 2 because it goes beyond a single keyword to a broad set of common phrasings.

3 / 3

Distinctiveness Conflict Risk

Has a clear niche (ToolUniverse biological-context integration after statistical analysis) with distinct triggers unlikely to fire for pure enrichment, statistical modeling, or literature-review skills; not generic enough to conflict with many skills.

3 / 3

Total

12

/

12

Passed

Validation

100%

Checks the skill against the spec for correct structure and formatting. All validation checks must pass before discovery and implementation can be scored.

Validation16 / 16 Passed

Validation for skill structure

No warnings or errors.

Repository
mims-harvard/ToolUniverse
Reviewed

Table of Contents

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