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tooluniverse-disease-research

Generate comprehensive disease research reports covering genetics (causal genes, GWAS, OMIM), pathways (Reactome, KEGG), drugs (existing therapies, repurposing candidates), clinical trials, epidemiology (prevalence, incidence), and phenotypes (HPO). Use for full disease overviews, comprehensive disease characterization, and orphan/rare-disease profiling.

56

Quality

63%

Does it follow best practices?

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SecuritybySnyk

Low

Low-risk findings worth noting

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tessl review fix ./plugin/skills/tooluniverse-disease-research/SKILL.md
SKILL.md
Quality
Evals
Security

Quality

Content

42%

Reviews the quality of instructions and guidance provided to agents. Good implementation is clear, handles edge cases, and produces reliable results.

A well-structured skill body with a clear report template, evidence-grading scheme, and synthesis questions, but it leans on motivational prose Claude doesn't need and delegates most executable detail to bundle files that are not present. The missing bundle files make progressive disclosure the weakest dimension.

DimensionReasoningScore

Conciseness

The body is mostly efficient and actionable, but it carries some unnecessary explanation Claude already knows (e.g. the 'LOOK UP, DON'T GUESS' preamble and 'When you're not sure... your first instinct should be to SEARCH') and conceptual scaffolding that could be trimmed, matching the score-2 'mostly efficient but could be tightened' anchor rather than the fully lean score-3 anchor.

2 / 3

Actionability

It provides concrete executable code for ZOOMA calls and a precise report template, but most dimensions only list tool names in a table ('See: tool_usage_details.md for complete tool calls') without complete executable calls, leaving key guidance incomplete — matching score-2 'some concrete guidance but incomplete'.

2 / 3

Workflow Clarity

The core workflow is sequenced (create file → research each dimension → update progressively → cite), but the progressive-update pattern is only shown as commented pseudocode rather than a real feedback loop, and there is no validation checkpoint verifying the report actually builds/cites correctly before finalizing, so it lands at score-2 'steps listed but validation gaps'.

2 / 3

Progressive Disclosure

The body relies heavily on external references (tool_usage_details.md, REPORT_TEMPLATE.md, RESEARCH_PROTOCOL.md, TOOLS_REFERENCE.md, EXAMPLES.md, plus a cross-skill script path), but none of these bundle files actually exist in references/, scripts/, or assets/ — the references are dangling with no verified structure, which is worse than the score-2 'references present but not clearly signaled' anchor and matches the disorganized/monolithic-with-broken-references end of the scale.

1 / 3

Total

7

/

12

Passed

Description

85%

Based on the skill's description, can an agent find and select it at the right time? Clear, specific descriptions lead to better discovery.

A strong description that explicitly states both capabilities and a 'Use for...' trigger clause with a well-defined disease-research niche. It is slightly held back by trigger-term quality that favors technical/database terminology over the natural phrases a user would say.

Suggestions

Add user-natural trigger phrases such as 'what do we know about a disease', 'disease overview', or 'research a condition' alongside the technical terms to improve trigger_term_quality.

Consider dropping or de-emphasizing parenthetical database names (OMIM, KEGG, HPO) in the description so the opening reads more like natural user language.

DimensionReasoningScore

Specificity

Lists multiple concrete actions with named data categories — 'covering genetics (causal genes, GWAS, OMIM), pathways (Reactome, KEGG), drugs (existing therapies, repurposing candidates), clinical trials, epidemiology (prevalence, incidence), and phenotypes (HPO)' — matching the score-3 anchor that lists multiple specific concrete actions.

3 / 3

Completeness

It answers 'what' ('Generate comprehensive disease research reports covering...') and 'when' with an explicit trigger clause ('Use for full disease overviews, comprehensive disease characterization, and orphan/rare-disease profiling.'), matching the score-3 anchor for clearly answering both what AND when.

3 / 3

Trigger Term Quality

It includes relevant domain keywords (disease, genetics, clinical trials, orphan/rare-disease) but leans on technical jargon and database names rather than natural phrasings a user would actually say, so it only partially matches the score-3 'natural terms users would say' anchor.

2 / 3

Distinctiveness Conflict Risk

The disease-research niche with named data sources and explicit triggers (full disease overviews, rare-disease profiling) carves a clear domain unlikely to conflict with unrelated skills, matching the score-3 clear-niche anchor.

3 / 3

Total

11

/

12

Passed

Validation

93%

Checks the skill against the spec for correct structure and formatting. All validation checks must pass before discovery and implementation can be scored.

Validation15 / 16 Passed

Validation for skill structure

CriteriaDescriptionResult

relative_links

Relative link issues: 5 missing

Warning

Total

15

/

16

Passed

Repository
mims-harvard/ToolUniverse
Reviewed

Table of Contents

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