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tooluniverse-polygenic-risk-score

Build and interpret polygenic risk scores (PRS) for complex diseases using GWAS summary statistics. Covers PRS construction (clumping/thresholding, PRS-CS), validation in independent cohorts, ancestry-aware adjustment, and clinical interpretation (population-relative risk, not absolute prediction). Use for PRS-based risk stratification.

64

Quality

75%

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SecuritybySnyk

Low

Low-risk findings worth noting

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tessl review fix ./plugin/skills/tooluniverse-polygenic-risk-score/SKILL.md
SKILL.md
Quality
Evals
Security

Low

Low-risk findings.

1 low severity finding. Worth noting, but not necessarily harmful.

Low

W011: Third-party content exposure detected (indirect prompt injection risk).

What this means

The skill exposes the agent to untrusted, user-generated content from public third-party sources, creating a risk of indirect prompt injection. This includes browsing arbitrary URLs, reading social media posts or forum comments, and analyzing content from unknown websites.

Why it was flagged

At runtime, the workflow calls ToolUniverse’s `gwas_get_associations_for_trait` to ingest GWAS association records (including free-text fields like study/trait/mapped gene/location strings) into the LLM-controlled parsing/build path, and those records are fetched from an external data source rather than fixed first-party metadata.

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Repository
mims-harvard/ToolUniverse
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Security analysis
Snyk

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