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tooluniverse-precision-oncology

Cancer treatment recommendations from molecular profile (mutations + cancer type + biomarkers) — FDA-approved + investigational therapies, resistance mechanisms, matching clinical trials, prognosis. Uses CIViC, ClinVar, OpenTargets, ClinicalTrials.gov. Use for tumor-board treatment recommendations, evidence-tiered actionability assessment, and FDA-precedent-driven therapy selection.

72

Quality

88%

Does it follow best practices?

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SecuritybySnyk

Low

Low-risk findings worth noting

SKILL.md
Quality
Evals
Security

Quality

Content

77%

Reviews the quality of instructions and guidance provided to agents. Good implementation is clear, handles edge cases, and produces reliable results.

A well-structured, highly actionable clinical workflow with clear phasing, mandatory validation steps, and concrete tool/parameter guidance. Its main weaknesses are heavy inline reference tables that inflate the body and reference files that are named but not actually shipped in the bundle.

Suggestions

Move the large biomarker-to-drug and resistance-mechanism mapping tables into TREATMENT_ALGORITHMS.md and keep only a brief pointer plus the hierarchy principle in SKILL.md.

Ship the referenced files (TOOLS_REFERENCE.md, API_USAGE_PATTERNS.md, TREATMENT_ALGORITHMS.md, REPORT_TEMPLATE.md, EXAMPLES.md, CHECKLIST.md) or remove the links, so progressive disclosure reflects the actual bundle.

De-duplicate parameter guidance: the Phase 0 'WRONG/CORRECT' table and the inline 'param: ...' notes repeat the same parameter names (condition, ensemblId) — consolidate into one place.

DimensionReasoningScore

Conciseness

Mostly efficient but the inline biomarker-to-drug mapping tables (NSCLC, Breast, Colorectal, Melanoma, tumor-agnostic) and resistance-mechanism lists are large reference data that could live in TREATMENT_ALGORITHMS.md rather than the body; the Phase 0 correction table also repeats parameter guidance already given later.

2 / 3

Actionability

Provides concrete, executable guidance: exact tool names with correct parameter names and examples ('condition', NOT 'disease'; 'ensemblId' camelCase; molecular_profile="EGFR C797S"), plus a worked cross-skill script invocation.

3 / 3

Workflow Clarity

Clear phased sequence (Phase 0–6) with explicit validation checkpoints — Phase 0 tool-verification table, MANDATORY FAERS/FDA calls with 'do NOT skip', and a 'LOOK UP DON'T GUESS' guard against assuming from memory.

3 / 3

Progressive Disclosure

Body signals one-level-deep references (TOOLS_REFERENCE.md, API_USAGE_PATTERNS.md, etc.) and points to a scripts file, but those reference files are not present in the bundle, so the disclosure structure is claimed but not actually realized on disk.

2 / 3

Total

10

/

12

Passed

Description

100%

Based on the skill's description, can an agent find and select it at the right time? Clear, specific descriptions lead to better discovery.

A high-quality description: third-person voice, concrete capabilities, named data sources, and an explicit 'Use for' trigger clause. It clearly communicates both what the skill does and when to invoke it without padding.

DimensionReasoningScore

Specificity

Lists multiple concrete actions: 'FDA-approved + investigational therapies, resistance mechanisms, matching clinical trials, prognosis' and names specific databases (CIViC, ClinVar, OpenTargets, ClinicalTrials.gov).

3 / 3

Completeness

Explicitly answers both what ('Cancer treatment recommendations from molecular profile...') and when via the 'Use for tumor-board treatment recommendations, evidence-tiered actionability assessment, and FDA-precedent-driven therapy selection' clause.

3 / 3

Trigger Term Quality

Covers natural terms users would say — 'cancer', 'tumor-board treatment recommendations', 'clinical trials', 'therapy selection', 'biomarkers' — plus domain-specific triggers like 'evidence-tiered actionability assessment'.

3 / 3

Distinctiveness Conflict Risk

Clear niche — precision oncology molecular-profile-driven treatment advice — with distinct triggers (tumor-board, FDA-precedent-driven therapy selection) unlikely to conflict with other skills.

3 / 3

Total

12

/

12

Passed

Validation

93%

Checks the skill against the spec for correct structure and formatting. All validation checks must pass before discovery and implementation can be scored.

Validation15 / 16 Passed

Validation for skill structure

CriteriaDescriptionResult

relative_links

Relative link issues: 6 missing

Warning

Total

15

/

16

Passed

Repository
mims-harvard/ToolUniverse
Reviewed

Table of Contents

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