Content
71%Weight 40%Scale 1-5Reviews the quality of instructions and guidance provided to agents. Good implementation is clear, handles edge cases, and produces reliable results.
A highly actionable, well-sequenced analysis workflow with concrete tool calls and explicit gating checkpoints. Its main weaknesses are the inlined advanced ThermoMPNN/SaaS material that should be split into a reference file and the absence of any progressive-disclosure references.
Suggestions
Move the optional 'ThermoMPNN instead of DynaMut2' section (including the five-vendor SaaS list) into a separate references file (e.g. references/THERMOMPNN.md) and replace it with a one-line pointer, improving both conciseness and progressive_disclosure.
Add explicit validate→fix→retry feedback loops for the fragile steps (e.g., Step 0 reference-residue mismatch and Step 5 PDB coverage checks) to lift workflow_clarity from 4 to 5.
Tighten Step 4's two parallel code paths into a single recommended path with the lower-level alternative as a brief note, reducing token cost without losing actionability.
| Dimension | Reasoning | Score |
|---|---|---|
Conciseness | Mostly efficient and free of beginner-concept padding, but the ~45-line optional ThermoMPNN section with a five-vendor SaaS list is substantial tangential material inlined in the main skill that could be tightened or moved to a reference; not the level-4 'minor trim' case. | 3 / 5 |
Actionability | Fully executable, copy-paste-ready tool calls with real parameters, tool names, and numeric thresholds (≥0.564, ΔlogP < −1, ddG > +1 kcal/mol) covering the common cases across all five signal types. | 5 / 5 |
Workflow Clarity | Seven clearly sequenced steps (Step 0–7) with explicit checkpoints (reference-residue assert, AlphaMissense benign branch, pLDDT gating, Step 7 confidence grading); just below 5 because error-recovery feedback loops in later steps are mostly implicit rather than explicit validate→fix→retry loops. | 4 / 5 |
Progressive Disclosure | Well-organized with clear section headers but no bundle files exist and there are no one-level-deep references, while the inlined optional ThermoMPNN/SaaS vendor content is material that clearly belongs in a separate reference file. | 3 / 5 |
Total | 15 / 20 Passed |