Non-coding/regulatory variant interpretation — GWAS association lookup, eQTL evidence (GTEx), chromatin state (ENCODE), regulatory variant scoring (RegulomeDB, CADD), and TF-binding disruption. Use for non-coding GWAS hit interpretation, eQTL-based gene assignment, and regulatory mechanism reasoning. Distinct from coding-variant tools.
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Low
Low-risk findings worth noting
Low
Low-risk findings.
1 low severity finding. Worth noting, but not necessarily harmful.
The skill exposes the agent to untrusted, user-generated content from public third-party sources, creating a risk of indirect prompt injection. This includes browsing arbitrary URLs, reading social media posts or forum comments, and analyzing content from unknown websites.
All runtime inputs described (e.g., `disease_trait` free-text) are used only as query parameters to first-party controlled-vocabulary/resource APIs/tools (GWAS Catalog via `gwas_search_associations`, GTEx, RegulomeDB, ENCODE, OpenTargets) rather than reading outsider-authored documents/feeds; the workflow does not ingest arbitrary free text from an outsider source without selecting specific items.
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