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opentargets-database

Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target identification.

61

Quality

73%

Does it follow best practices?

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Adds up to 20 points to the overall score

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SecuritybySnyk

Low

Low-risk findings worth noting

Fix and improve this skill with Tessl

tessl review fix ./backend/cli/skills/databases/opentargets-database/SKILL.md
SKILL.md
Quality
Evals
Security

Quality

Content

78%Weight 40%Scale 1-5

Reviews the quality of instructions and guidance provided to agents. Good implementation is clear, handles edge cases, and produces reliable results.

The body is highly actionable with executable examples and a well-structured progressive-disclosure layout pointing to real reference files. The main improvement area is conciseness, as some explanatory prose and workflow redundancy could be tightened.

Suggestions

Tighten the Overview and 'Common Workflows' sections; the four named workflows overlap significantly with the numbered core workflow and could be condensed or merged.

Remove or relocate definitions Claude already knows (e.g., clinical trial phase meanings, what association scores are) unless they carry skill-specific interpretation.

Add a short error-handling checkpoint (e.g., how to react when execute_query raises or returns empty results) to round out workflow clarity for API-failure cases.

DimensionReasoningScore

Conciseness

Mostly efficient with code blocks and field lists, but contains explanatory prose (overview, clinical-phase definitions, best-practice narratives) and overlap between the core workflow and 'Common Workflows' that could be trimmed.

3 / 5

Actionability

Provides copy-paste-ready Python code with real function signatures, realistic arguments, and example return structures covering the common cases across all entity types.

5 / 5

Workflow Clarity

A clear numbered core workflow plus four detailed scenario workflows give strong sequencing; minor gap is the lack of explicit error-recovery checkpoints for API failures, though the skill is read-only so no destructive-validation cap applies.

4 / 5

Progressive Disclosure

SKILL.md serves as a concise overview with well-signaled, one-level-deep references to real files (api_reference.md, evidence_types.md, target_annotations.md) and a bundled script, making navigation easy.

5 / 5

Total

17

/

20

Passed

Description

67%Weight 40%Scale 1-5

Based on the skill's description, can an agent find and select it at the right time? Clear, specific descriptions lead to better discovery.

The description is specific and distinct, enumerating several concrete capabilities tied to a clearly named platform. Its main weakness is the absence of an explicit 'Use when...' trigger clause, which limits completeness and natural trigger-term coverage.

Suggestions

Add an explicit 'Use when...' clause naming natural user phrasings such as 'Use when identifying therapeutic drug targets, evaluating target tractability, or finding target-disease evidence'.

Include common synonyms and trigger phrases users would actually say (e.g., 'drug target prioritization', 'GWAS evidence lookup', 'druggability assessment').

Consider mentioning the GraphQL/programmatic access angle since it distinguishes how this skill differs from a generic database look-up.

DimensionReasoningScore

Specificity

Lists multiple concrete actions — 'target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs' — giving comprehensive coverage of the skill's capabilities.

5 / 5

Completeness

Provides a clear 'what' via enumerated capabilities, but offers no explicit 'when to use' trigger clause, which caps completeness at 3 per the judging guideline.

3 / 5

Trigger Term Quality

Contains relevant domain keywords (target-disease associations, tractability, known drugs) but lacks natural trigger phrases a user would say and common synonyms; no 'Use when...' phrasing present.

3 / 5

Distinctiveness Conflict Risk

Names a specific platform (Open Targets) and a distinct niche (therapeutic target identification), making it clearly distinguishable with minimal conflict risk against other skills.

5 / 5

Total

16

/

20

Passed

Validation

87%

Checks the skill against the spec for correct structure and formatting. All validation checks must pass before discovery and implementation can be scored.

Validation14 / 16 Passed

Validation for skill structure

CriteriaDescriptionResult

metadata_version

'metadata.version' is missing

Warning

frontmatter_unknown_keys

Unknown frontmatter key(s) found; consider removing or moving to metadata

Warning

Total

14

/

16

Passed

Repository
synthetic-sciences/openscience
Reviewed

Table of Contents

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