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opentargets-database

Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target identification.

59

Quality

70%

Does it follow best practices?

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SecuritybySnyk

Low

Low-risk findings worth noting

Fix and improve this skill with Tessl

tessl review fix ./backend/cli/skills/databases/opentargets-database/SKILL.md
SKILL.md
Quality
Evals
Security

Quality

Content

72%Weight 40%Scale 1-3

Reviews the quality of instructions and guidance provided to agents. Good implementation is clear, handles edge cases, and produces reliable results.

The content is highly actionable with executable examples and good progressive disclosure to real reference files, but it is somewhat verbose and its workflows lack explicit validation checkpoints.

Suggestions

Tighten verbose sections — consolidate the 9 'When to Use' bullets and trim the descriptive overview prose to respect token budget.

Add a brief validation checkpoint to the core workflow (e.g., confirm a returned Ensembl/EFO ID is non-empty before querying details) to lift workflow clarity.

DimensionReasoningScore

Conciseness

The body is mostly efficient domain-specific guidance and code, but sections like the 9-bullet 'When to Use', four full multi-step workflows, and descriptive overview prose could be tightened.

2 / 3

Actionability

Provides fully executable, copy-paste-ready code with imports, real function calls, and documented return shapes (e.g., search_entities("BRCA1", entity_types=["target"])) matching the executable anchor.

3 / 3

Workflow Clarity

Workflows are clearly numbered and sequenced, but there are no explicit validation checkpoints or error-recovery feedback loops, leaving checkpoints implicit.

2 / 3

Progressive Disclosure

The SKILL.md is a clear overview with well-signaled one-level-deep references to real files (api_reference.md, evidence_types.md, target_annotations.md) and the helper script, with content appropriately split.

3 / 3

Total

10

/

12

Passed

Description

67%Weight 40%Scale 1-3

Based on the skill's description, can an agent find and select it at the right time? Clear, specific descriptions lead to better discovery.

The description is specific and clearly distinguishable via the named platform, but it omits an explicit 'Use when' trigger clause and leans on some technical jargon, which caps completeness and trigger-term quality at 2.

Suggestions

Add an explicit trigger clause such as 'Use when identifying therapeutic drug targets, assessing target tractability/safety, or gathering target-disease evidence' to satisfy the 'when' half of completeness.

Soften jargon by pairing technical terms with natural phrasings users would actually say (e.g., 'druggability' alongside 'tractability').

DimensionReasoningScore

Specificity

Lists multiple concrete actions ('Query ... target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs') matching the multi-action anchor.

3 / 3

Completeness

Clearly states what the skill does but provides no explicit 'Use when...' trigger guidance; the trailing 'for therapeutic target identification' is a purpose, not a trigger, capping completeness at 2.

2 / 3

Trigger Term Quality

Contains relevant domain terms ('drug target discovery', 'known drugs') but mixes in technical jargon ('tractability/safety data, genetics/omics evidence') and lacks natural 'Use when' phrasing, missing common variations.

2 / 3

Distinctiveness Conflict Risk

Names a specific named resource ('Open Targets Platform') giving it a clear niche unlikely to conflict with other skills.

3 / 3

Total

10

/

12

Passed

Validation

87%

Checks the skill against the spec for correct structure and formatting. All validation checks must pass before discovery and implementation can be scored.

Validation14 / 16 Passed

Validation for skill structure

CriteriaDescriptionResult

metadata_version

'metadata.version' is missing

Warning

frontmatter_unknown_keys

Unknown frontmatter key(s) found; consider removing or moving to metadata

Warning

Total

14

/

16

Passed

Repository
synthetic-sciences/openscience
Reviewed

Table of Contents

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