Biological data toolkit. Sequence analysis, alignments, phylogenetic trees, diversity metrics (alpha/beta, UniFrac), ordination (PCoA), PERMANOVA, FASTA/Newick I/O, for microbiome analysis.
72
70%
Does it follow best practices?
Impact
63%
2.86xAverage score across 3 eval scenarios
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The risk profile of this skill
Fix and improve this skill with Tessl
tessl review fix ./skills/bio/scikit-bio/SKILL.mdPhylogenetic tree construction methods
nj() for neighbor joining
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upgma() for UPGMA
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100%
GME/BME scalability note
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DistanceMatrix class
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100%
Patristic distances
50%
50%
Cophenetic matrix
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62%
Robinson-Foulds distance
33%
66%
PCoA on distance matrix
30%
100%
Newick output
100%
100%
uv install command
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100%
Sequence class selection and alignment methods
DNA class usage
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100%
RNA class for transcription
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100%
Protein class for translation
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100%
FASTQ quality via positional_metadata
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20%
local_pairwise_align_ssw for DNA
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0%
StripedSmithWaterman for protein
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Affine gap penalties
60%
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Degap before realignment
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Generator-based FASTQ reading
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uv install command
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100%
Diversity analysis best practices
Integer counts
100%
100%
Faith's PD tree param
50%
70%
UniFrac tree param
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PERMANOVA permutations
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100%
PERMDISP alongside PERMANOVA
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0%
PCoA on distance matrix
100%
100%
partial_beta_diversity for pairs
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0%
Alpha result as Series
100%
100%
Beta result as DistanceMatrix
100%
100%
uv install command
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100%
Permutation test 999+
100%
100%
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