Claude Science's own session database schema and SDK surface for introspection via host.query(). Load this when you need to query your own conversation history, token usage, cost accounting, execution log, or artifact metadata beyond what host.frames()/host.artifacts() provide — e.g. "how many tokens has this session used", "what was my last tool call", "list every file I've written", "where are messages stored", "what tables can I query", "inspect frames.context_data", or any time you're about to PRAGMA-probe the Claude Science metadata DB to discover its schema.

This skill should be used when the user asks to "migrate from OpenAI Apps SDK", "convert OpenAI App to MCP", "port from window.openai", "migrate from skybridge", "convert openai/outputTemplate", or needs guidance on converting OpenAI Apps SDK applications to MCP Apps SDK. Provides step-by-step migration guidance with API mapping tables.

Runs the DEFT embed-then-mine workflow for VCN AOI iterations — embeds the gap-analysis target parquet, embeds a source pool, and mines nearest-neighbour source images for downstream augmentation. Use as the immediate next step after `tao-route-visual-changenet-samples` when expanding a real-image augmentation queue from the mining subset.

Use this skill when deploying, operating, or integrating the VSS 3.2 GA RT-Embed Video Embedding microservice. Covers Docker Compose bring-up, GPU and storage prerequisites, the `/v1` REST API (file uploads, text and video embeddings, live RTSP streams, health and metrics), Redis/Kafka/OTel integration, common failure modes, and teardown.

Iteratively optimize cuTile kernel performance through systematic profiling, bottleneck analysis, IR comparison, and targeted tuning. Covers tile sizes, occupancy, autotune configs, TMA, latency hints, persistent scheduling, num_ctas, flush_to_zero, and IR-level debugging. Use when asked to "optimize cutile kernel", "improve kernel perf", "tune cutile performance", "make kernel faster", or iteratively benchmark and refine a cuTile GPU kernel in the TileGym project.

Run the canonical NVIDIA AOI three-phase training pipeline — Phase 1 AutoML baseline (HPO), Phase 2 DEFT loop (RCA → SDG → mining → plain-train retrain), Phase 3 AutoML refinement on the DEFT-augmented dataset. Use when the user asks to "run the AOI workflow", "fine-tune my PCB AOI model end-to-end", "improve my AOI ChangeNet model", or "AOI workflow with AutoML" request — route here instead of tao-run-deft-aoi directly unless the user explicitly asks for the DEFT loop ONLY (e.g. "run JUST the DEFT loop", "skip AutoML, only DEFT"). Also handles the same three-phase pattern for non-AOI DEFT applications — AutoML baseline then DEFT loop warm-started from AutoML's winning HPs then post-DEFT AutoML refinement on the iteration-augmented dataset. Trigger phrases include "run the AOI workflow", "AOI end-to-end", "AutoML + DEFT", "AutoML then DEFT", "tune hyperparameters then DEFT", "DEFT with AutoML at both ends", "warm-start DEFT", "improve my AOI model".

Use when the user wants to orchestrate defect image generation with NVIDIA Cosmos AnomalyGen (Cosmos-Predict2-derived) on OSMO for PCBA, metal surface, and glass inspection. The Day 0 path handles cold-start with USD-to-ROI, image-edit augmentation, and AnomalyGen to create initial PCBA datasets. The Day 1 path performs inference and labeling on real images. This skill helps with first-time asset setup, creation of finetuning checkpoints, and configuring deployment. Trigger keywords: defect image generation, dig workflow, dig pipeline, defect image detection workflow, aoi pipeline, aoi anomalygen, usd2roi anomalygen, day 0 pcba, day 1 pcba, day 1 real-photo alignment, day 1 manual roi, metal surface anomaly, glass defect, anomalygen finetune, setup_pcb, setup_metal, setup_glass, setup_pretrained, dig setup, dig datasets, dig pretrained checkpoint, dig image-edit endpoint, cosmos defect generation, cosmos-predict2 defect, cosmos-anomalygen, cosmos predict2 finetune.

Four-step image referring-expression pipeline: turns images plus KITTI bounding-box labels into region descriptions, scene captions, grounded referring expressions, and (optionally) verified expressions via VLM distillation. Use when the user wants to generate referring-expression annotations from images with KITTI labels, build region descriptions, produce grouped grounding phrases tied to bboxes, run a double-check verification pass on grounding expressions, auto-label traffic / scene images for referring datasets, or run the image_referring_expression pipeline. Triggers include 'referring expression', 'region description', 'KITTI labels', 'spatial relationship annotation', 'auto-label image referring expression', 'image_referring_expression'.

Cache and refresh remote git repositories under ~/.cache/checkouts/<host>/<org>/<repo> so future references can reuse a local copy. Use this skill when the user points you to a remote git repository as reference or you encountered a remote git repo through other means.

用 21 套内置中文 PPT 模板（或用户自带的 .pptx 模板）生成与编辑 PowerPoint 演示文稿：只替换文字、不破坏原排版/配色/字号，内置按文本框尺寸的出框检测与同级标题字号一致校验；也支持完全原创的简洁版式。当用户要"做 / 生成 / 制作 / 编辑一份 PPT / 演示文稿 / 幻灯片 / .pptx"，或需要工作汇报、年终与季度总结、述职竞聘、项目复盘、开题答辩、商务提案、教学课件、数据可视化等成品 PPTX 时使用。Use when the user wants to create or edit a PowerPoint / PPT / slides / .pptx deck, pick from built-in templates, or apply their own template without breaking the layout.

Run pathway and gene-set enrichment analysis on gene lists or ranked gene data, then interpret the results. Use whenever the user has a set of genes (differentially expressed genes from PyDESeq2/Scanpy, CRISPR-screen hits, cluster marker genes, proteomics hits) and wants to know which biological pathways, GO terms, or gene sets are over-represented or enriched. Covers over-representation analysis (ORA / Enrichr / Fisher / hypergeometric), ranked Gene Set Enrichment Analysis (GSEA / preranked), single-sample scoring (ssGSEA/GSVA), and functional profiling via gseapy, g:Profiler, Enrichr libraries, MSigDB, GO, KEGG, Reactome, and WikiPathways — plus gene-ID mapping, choosing the right background universe, multiple-testing correction, redundancy reduction, dotplots/enrichment maps, and publication-ready tables. Use this for "pathway analysis", "enrichment analysis", "GO enrichment", "KEGG/Reactome pathways", "GSEA", "over-representation", "functional annotation", or "what pathways are my genes in".

Query live pathogen genomic surveillance data through the GenSpectrum LAPIS API to find which viral lineages are circulating now, how fast they are growing, and what mutations they carry. Use whenever a question depends on the current state of a pathogen population rather than on remembered facts - which SARS-CoV-2 variant is dominant, whether a Pango lineage is still designated or has been withdrawn, what clade or genotype of H5N1 is in a host or region, whether a PCR primer or assay target still matches circulating sequence, or how a lineage's prevalence has moved week to week. Triggers include "variant surveillance", "genomic surveillance", "what variant is circulating", "dominant variant", "Pango lineage", "lineage prevalence", "growth advantage", "SARS-CoV-2 variant", "XFG", "clade 2.3.4.4b", "H5N1 genotype", "influenza clade", "RSV/mpox/measles/dengue lineage", "CoV-Spectrum", "LAPIS", "Nextclade", "pango-designation", and any request to report what a pathogen population looks like today.

Build, run, and debug Nextflow data pipelines and nf-core workflows end to end. Use whenever the user mentions Nextflow, nf-core, .nf files, nextflow.config, DSL2, processes/channels/operators, samplesheets, or wants to run a community pipeline (e.g. nf-core/rnaseq, nf-core/sarek), write or test a module/subworkflow with nf-test, configure executors/containers (Docker, Singularity/Apptainer, Conda, Wave), scale a workflow to HPC/SLURM or cloud (AWS Batch, Google Batch, Azure, Kubernetes), or debug a failed/-resume run. Make sure to use this skill for any reproducible scientific/bioinformatics workflow work even if the user does not say the word "Nextflow", and for authoring nf-core-compliant pipelines, modules, configs, and linting.

Submit and manage protocols on Ginkgo Bioworks Cloud Lab (cloud.ginkgo.bio), a web-based interface for autonomous lab execution on Reconfigurable Automation Carts (RACs). Use when the user wants to run protein expression and purification (cell-free, E. coli, or Pichia), HiBiT or A280 or LabChip quantification, IVT mRNA/circRNA synthesis, thermal shift / developability assays, Echo-MS enzyme or analyte methods, SPR target onboarding, fluorescent pixel art, or otherwise interact with Ginkgo Cloud Lab services. Covers protocol selection, input preparation, pricing, and ordering workflows.

Install or remove third-party openscience skills from a public git repository. Use when the user says "add this skill <url>", "install skill <url>", or "remove skill <namespace>". The skill runs locally via `openscience skill add|list|remove`, fetches the repo, runs a 6-layer safety gate (regex + server-side Haiku classifier), prompts the user to confirm, then writes the skills to ~/.openscience/installed-skills/ and uploads to the dashboard for cross-machine sync.

Investigate and triage CI failures for dotnet/macios from Azure DevOps build URLs. Use this skill whenever the user shares a DevOps build link, asks about CI failures, wants to understand why a build failed, or asks to investigate test failures on any platform (iOS, tvOS, macOS, Mac Catalyst). Also use when the user says things like "CI is red", "tests are failing", "build broke", or "what happened in CI".

Use when creating data visualizations for papers - generates publication-quality plots with top-journal color schemes

Use when wiring mem0() from @tanstack/ai-memory/mem0 — a hosted memory adapter that talks to a mem0 server over plain HTTP (no SDK peer). Requires a running mem0 server.

Use when wiring memoryMiddleware from @tanstack/ai-memory into a chat() call — covers the recall/save adapter contract, scope shape and server-side scope security, the recall-inject / deferred-save lifecycle, choosing an adapter (inMemory, redis, hindsight, mem0, honcho), and devtools events.

Sweep open (or listed) PRs with up to 100 parallel agents: security-scan outside contributors, rebase onto main when behind (push --force-with-lease), approve pending first-time-contributor CI when relevant, optionally rebase in-house PRs, and report who should review. Supports full, changed-only, behind-only, and conflict-only scopes for cheap daily runs. Use when the user runs /pr-sweep (or /pr-inbound-sweep), or asks to "sweep PRs", "sweep inbound PRs", "security-check outside PRs", "rebase outsider PRs", "rebase our PRs", "approve waiting CI on PRs", "daily PR sweep", or "prep external PRs for review".