Use when writing or reviewing C# code in this repo that calls Deepgram Text-to-Speech. Covers `ClientFactory.CreateSpeakRESTClient()` with `ToStream` / `ToFile`, and `ClientFactory.CreateSpeakWebSocketClient()` with `Connect`, `SpeakWithText`, `Flush`, and streaming `AudioResponse` events. Use `deepgram-dotnet-voice-agent` for full-duplex assistants instead of one-way synthesis.

Exhaustive multi-source research on a topic with attributed claims, a mandatory adversarial counterpoint, and an open-questions list. Analyst-grade — claims are tagged with source class (primary / expert / secondary / market signal) and confidence, contradicting sources are named rather than averaged. Use when the cost of being wrong exceeds an hour of research. Triggers: "deep research X", "DD on Y", "build me a memo on Z", "contrarian take on X".

Weekly funding round tracker across configurable verticals (AI, crypto, prediction markets, agentic infrastructure, etc.). Primary-source-required (Form D, press release, or verified founder/firm post) — filters re-announcements and rumored rounds. Per round: lead, size, valuation if disclosed, what they do, why now, and the sharpest risk. Triggers: "this week in funding", "deal flow", "who raised this week", "crypto funding rounds", "AI funding tracker".

Author economical visual tests — full visual coverage in the fewest billable snapshots. Applies to any per-snapshot visual tool (UI Verify, Chromatic, Percy, Playwright screenshots), which all bill and diff per rendered story/test. Use when a component's variants/states are exploding into one snapshot per combination, when the visual-testing bill or noise is driven by snapshot count, or when writing new stories/captures and you want the cheapest layout that still covers every variant. Covers gallery/matrix stories, data-driven states, and the coarse-granularity tradeoff.

Add, translate, or audit TinyWorld UI strings across English/French/Chinese/Spanish. Use when adding user-facing gameplay text, when `npm run i18n:check` fails, when a string shows up in English in a non-English locale, or when adding a new language. No translation API — Codex does the translating directly, using the established glossary for consistency.

Drug-combination synergy analysis — quantify whether two drugs together are synergistic, additive, or antagonistic using the standard reference models (Bliss independence, HSA / highest single agent, Loewe additivity, ZIP, and the Chou-Talalay Combination Index). Use when you have measured single-drug and combination effects (inhibition/viability) and need a synergy score. Explains which model to use, what data each one needs, and how to read the score. NOT for looking up pre-computed synergy in a database (use the SYNERGxDB tool / cell-line-profiling skill).

Pharmacokinetic (PK) analysis of concentration-time data — non-compartmental analysis (NCA) for Cmax, Tmax, AUC (0-t and 0-∞), terminal half-life, clearance (CL), volume of distribution (Vd), MRT, and absolute bioavailability (F). Also one-compartment fitting. Use when you have plasma/serum drug concentrations over time after a dose and need PK parameters, or to compute bioavailability from IV + oral AUCs. NOT for ADMET property prediction from structure (use tooluniverse-admet-prediction).

Compute and interpret validated bedside clinical risk scores and pretest probabilities for an INDIVIDUAL patient — pick the right score for the scenario, gather inputs, run the deterministic calculator tool, and read the result against an interpretation table. Covers CHA2DS2-VASc (AF stroke risk), HAS-BLED (bleeding on anticoagulation), CURB-65 (pneumonia severity / admit decision), qSOFA (sepsis screen), Child-Pugh + MELD-Na (cirrhosis severity / transplant priority), Wells DVT and Wells PE (VTE pretest probability), ASCVD (10-year cardiovascular risk / statin decision), and eGFR CKD-EPI (kidney function / drug dosing). Use when asked things like "stroke risk for this AF patient", "should this patient be anticoagulated", "pneumonia severity — admit or not?", "sepsis screen this patient", "DVT/PE pretest probability", "10-year cardiovascular risk", "cirrhosis severity / MELD score", or "eGFR / kidney function". Pairs CHA2DS2-VASc with HAS-BLED to weigh anticoagulation. NOT for...

Guided journey from a business with lucky months to a repeatable growth engine that produces a forecast. Orchestrates nine skills phase by phase - one-page-marketing, hundred-million-offers, predictable-revenue, contagious, influence-psychology, crossing-the-chasm, cold-start-problem, lean-analytics, negotiation - asking the user questions at every decision point and recording results in the project docs/ folder (MARKETING.md, OFFER.md, METRICS.md, GROW-BUSINESS-PLAN.md) so the journey resumes across sessions. Use when the user wants to build a marketing and sales system, manufacture predictable pipeline, engineer word-of-mouth and referrals, or says 'revenue is real but lumpy and I need growth that repeats'. If the offer, retention, or operations underneath are broken, run improve-business first; with no paying customers yet, start with create-business; when the product itself must carry the growth loops, use grow-app. For one framework in isolation, invoke that skill directly.

Use to extend an existing agent project with memory, app integration, VPC, multi-agent, migration, model, browser, code interpreter, payments, or resource removal. Triggers: "add memory", "remember across sessions", "call agent from app", "invoke agent from code", "agent auth", "streaming", "VPC", "VPC connectivity", "can't reach from VPC", "multi-agent", "A2A", "A2A auth", "orchestrator not delegating", "specialist not called", "migrate Bedrock Agent", "migration issue", "change model", "browser tool", "code interpreter", "delete agent", "tear down", "agentcore remove", "cross-account memory", "add payments capability to my agent", "wire payments plugin", "integrate x402 payments with the agent I'm building", "add MPP payments", "Machine Payments Protocol". External APIs via Gateway: use agents-connect. New project: use agents-get-started. CLI/dev-server errors: use agents-debug. Runtime x402/MPP payments: use agents-pay. Migration-specific Strands vs LangGraph routes here.

Performs a full AWS Well-Architected Framework review evaluating every framework question across all pillars discovered from the live AWS documentation by analyzing code, IaC, and configurations to produce evidence-backed findings with Eisenhower-prioritized remediation. Supports full reviews (every framework best practice with BP ID citations), quick reviews (question-level), pillar-scoped reviews, score-mode reviews (a maturity scorecard with per-pillar scores and filtered findings), and lens-specific reviews using lenses discovered from the live AWS documentation. Triggers on mentions of Well-Architected review, WA review, WAR, pillar assessment, architecture review across pillars, workload assessment, cloud readiness evaluation, or a Well-Architected score, grade, or scorecard request. Does not apply to single-pillar deep-dives, learning WA concepts, ADRs, or migration readiness assessments.

Use when deploying your agent to AWS, or when a deploy has failed. Handles pre-flight validation, CDK/IAM/quota error diagnosis, version management, rollback, and canary deployments. Triggers on: "deploy my agent", "agentcore deploy", "deploy failed", "CDK error", "rollback", "canary deploy", "pin version", "redeploy", "deploy stuck". Not for production hardening — use agents-harden. Not for adding capabilities before deploy — use agents-build or agents-connect. Not for VPC configuration errors — use agents-build.

Diagnoses a bug, error, stack trace, regression, or unexplained behavior and publishes the evidence-backed root cause to GitHub. Use when the user says "debug this", "find the root cause", provides a bug report or stack trace, asks to investigate a GitHub issue, or invokes /prp-debug. Defaults to commenting on the matching open issue or creating one when none exists.

Runs the detached, resumable PRP pipeline in fresh headless CLI sessions, cycling plan, implementation, PR, review, and corrections with persisted state and safety bounds. Use only when the user explicitly asks to "run the full PRP loop", "run this detached", "continue across context windows", use headless autonomous execution, resume a saved loop, or invokes $prp-loop. Use prp-issue for ordinary end-to-end delivery.

Creates GitHub issues from conversations, findings, or ideas and runs the precondition check before a planning-capable agent starts work. Use when the user asks to "create an issue from this", "turn this into an issue", "check whether issue #42 is agent-ready", "check this issue before automation", "audit this issue contract", "update this issue to make it agent-ready", or invokes $prp-issue-contract.

Deep startup profiling for OneKey mobile — per-module JS factory timings, HBC I/O/parse breakdown, per-segment timings. Gated behind the single env var `ONEKEY_STARTUP_PROFILE=1`. Zero overhead when disabled (default). Use when diagnosing cold-start regressions, sizing main.bundle parse cost, finding slow modules, measuring segment load, or auditing what a 1.7s `require('./App')` actually contains. Triggers on: startup profile, 启动性能分析, module timing, HBC parse time, segment timing, require cost, StartupProfile, ONEKEY_STARTUP_PROFILE, __d patcher, inline-requires.

Guides work on the Figma I/O package (@grida/io-figma, packages/grida-canvas-io-figma/). Covers the fig-kiwi binary parser, Kiwi→REST→Grida conversion pipeline, fig2grida CLI, REST API JSON conversion, and testing with clipboard/fig/REST fixtures. Use when adding node type support, fixing conversion bugs, extending fig2grida, working on the fig-kiwi parser, writing tests for Figma import, or debugging clipboard paste failures after a Figma update.

Create C# bindings for Apple frameworks in dotnet/macios. USE FOR: binding new APIs, implementing .todo file entries, creating Xcode SDK bindings, binding AVFoundation/UIKit/AppKit or any Apple framework, "bind this framework", "implement these APIs". DO NOT USE FOR: Xcode beta version bumps (use macios-xcode-beta-update skill), CI failure investigation (use macios-ci-failure-inspector skill).

Control a real browser to navigate pages, click, type, fill forms, inspect rendered UI, take screenshots, or record video. Load only when the user asks to open or automate a browser, interact with or test rendered page UI, scrape a site that needs browser execution, or capture a browser screenshot or video. Do not load for backend logs, traces, API or stream events, source-code inspection, or plain HTTP or web research that does not require a browser.