One-time setup skill that builds a personalized inbox triage knowledge base via interactive interview. Interviews the user about their email patterns, business context, reply style, and priorities using grill-me discipline (one question at a time, forcing format where possible, dependency-ordered, each question explains why I'm asking), then generates the knowledge base files that power the companion 'inbox-triage' skill. Run this once before using inbox-triage for the first time. Re-run when business, pricing, or priorities change significantly. Triggers: 'set up my inbox', 'configure inbox triage', 'set up my email system', 'configure email triage', 'build my email knowledge base', 'initialize email management', 'set up inbox triage', 'onboard email triage', or any variation where someone wants to get the email triage system running for the first time.

Builds clear, executable, and auditable inclusion and exclusion criteria for biomedical and clinical research protocols. Always use this skill when a user needs to translate a target population into operational screening rules tied to chart fields, time windows, tests, procedures, prior therapies, exclusions, and reviewable edge cases. Focus on protocol-stage precision, ambiguity reduction, auditability, and screening reproducibility rather than generic study design advice.

Runs the human-verification lane of an agent loop, and proves review happened before work is called done. Builds a single-file HTML review page, collects batched feedback as a structured artifact instead of chat prose, and runs a gate that refuses to close while a BLOCKER is open, the reviewer is unnamed, or nobody has reviewed at all. Use when a plan, spec, RFC, report, landing page, migration, or any irreversible action needs human sign-off before shipping, or on requests such as 'get sign-off', 'have someone check this', 'hold until reviewed', 'needs approval first'. NOT for making AI text sound human (use content-humanizer or behuman). NOT for reviewing code diffs (use md-review or code-reviewer).

Show DAG state, agent progress, and branch status for an AgentHub session. Use when the user runs /hub:hub-status or asks how the AgentHub agents are doing.

Generates complete phenotype-scoring bioinformatics research designs for any disease context and any user-defined phenotype, pathway, process, signature, or molecular program. Use when a study centers on gene-set or feature-set definition, intersection with DEGs or candidate features, phenotype scoring, feature selection, diagnostic or stratification assessment, immune or cellular-resolution interpretation, network analysis, and optional orthogonal validation. Covers five study patterns (signature discovery, phenotype scoring, feature selection, immune/cellular interpretation, multi-layer validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

Create a new AgentHub collaboration session with task, agent count, and evaluation criteria. Use when the user runs /hub:hub-init or asks to start a multi-agent competition on a task.

Designs a realistic, execution-aware biomedical study version under explicit constraints of samples, time, budget, data access, lab capacity, team skill, and validation resources. Always use this skill when the user has a real study idea, a candidate route, or a partially framed project but cannot assume ideal conditions. If critical feasibility inputs are missing, first clarify what resources are currently available, what resources may be obtainable, and what resources are realistically unavailable. Do not invent access, capabilities, collaborations, or validation resources. Focus first on feasibility-constrained study framing, route narrowing, dependency control, and minimum viable study design.

Orchestrate free opencode workers from Claude Code to cut token costs. Use when delegating grunt work to a single worker or a parallel swarm (scout/coder/tester) with worktree isolation, benchmarking against opencode, or when the user says "spawn a worker", "swarm", "delegate to opencode", or "/oc".

Helm chart development agent skill and plugin for Claude Code, Codex, Gemini CLI, Cursor, OpenClaw — chart scaffolding, values design, template patterns, dependency management, security hardening, and chart testing. Use when: user wants to create or improve Helm charts, design values.yaml files, implement template helpers, audit chart security (RBAC, network policies, pod security), manage subcharts, or run helm lint/test.

/em:hard-call — Framework for decisions with no good options. Use when every option is painful and a structured 10/10/10 + regret-minimization pass is needed — e.g. choosing between a layoff and a down round, or killing a beloved product line.

Generates complete FAERS-style pharmacovigilance disproportionality research designs from a user-provided drug class, comparator strategy, adverse-event domain, and patient-group stratification. Always use this skill whenever a user wants to design, plan, or build a spontaneous-report safety signal study using FAERS or a similar pharmacovigilance database, especially when the article logic includes product selection, indication-group stratification, MedDRA-based adverse-event extraction, serious-case filtering, suspect-drug and concomitant-exclusion logic, reporting odds ratio analysis, comparator-drug benchmarking, cross-drug comparison, and cautious signal interpretation without causal overclaiming. Covers five study patterns (single-drug disproportionality workflow, multi-drug class comparison workflow, indication-stratified workflow, comparator-controlled signal screening workflow...

Compact the current conversation into a handoff document for another agent to pick up. Save to a user-configured location (OS temp, home folder, or per-project .handoff/), redact secrets before write, suggest skills for the next session, and auto-load the latest handoff on the next SessionStart. First-run setup asks where to save so the project folder never gets cluttered. Use when the user says 'hand this off', 'handoff doc', 'summarize this for a new session', 'compact this conversation', 'I'm ending this session', 'pick this up later', or any variation signaling intent to pass work to a fresh agent. Also trigger on implicit signals: the user announcing they're switching machines, ending the day mid-task, or context is growing long without a natural stopping point.

Designs primary, secondary, and exploratory endpoints for biomedical and clinical research protocols. Always use this skill when a user needs to translate study aims into operational endpoint definitions with event rules, assessment timing, composite logic, interpretability, and protocol-stage auditability. Focus on endpoint precision, feasibility, clinical meaning, ambiguity reduction, and implementation readiness rather than generic study design advice.

Docs-anchored grilling session — challenges a plan against the project's existing language (CONTEXT.md) and recorded decisions (docs/adr/), and updates those files inline as terminology and decisions crystallise. Use when user wants to stress-test a plan against documented domain language, or mentions "grill with docs".

Interview the user relentlessly about a plan or design until reaching shared understanding, resolving each branch of the decision tree. Use when user wants to stress-test a plan, get grilled on their design, or mentions "grill me".

Generates complete dual-disease shared-transcriptome biomarker and hub-gene research designs from a user-provided disease pair and shared-biology direction. Always use this skill whenever a user wants to design, plan, or build a non-oncology two-disease transcriptome study centered on per-disease differential expression, shared-signal intersection or concordance, PPI-based hub-gene prioritization, diagnostic evaluation across both diseases, immune infiltration context, pathway interpretation, and optional orthogonal validation. Covers five study patterns (shared-DEG-first workflow, hub-gene-first shared-biomarker workflow, hybrid shared-biomarker compression workflow, immune-context shared-biomarker workflow, orthogonal validation workflow) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path...

NIH grant research skill for clinical researchers. Grill-me intake (research idea + career stage + preliminary data + environment + submission posture + known institute targets) locks down the funding strategy before any search runs. Runs a 5-facet Consensus positioning analysis (with draft Significance/Innovation language), maps the research to the right NIH institutes and study sections via RePORTER, finds NOSIs and funded overlap, and produces an editable Word document (.docx) with budget/scope-aware mechanism recommendations, submission timelines, and a mandatory program officer recommendation. Use when the user asks about research funding or makes any grant-related request (e.g., 'grants for [topic]', 'find grants for my research idea', 'what grants match my research', 'help me find NIH funding', 'grant opportunities for my research'). NIH-only scope — non-NIH funders (PCORI, DOD CDMRP, VA, foundations) are out of scope and flagged at intake.

Phase 3 of building a Claude Managed Agent — the bounded grade→iterate loop. Define a CMA outcome (a required markdown rubric graded by an isolated grader), read each verdict, decide the next move (sharpen / re-run / promote to schedule), and once a version passes, run held-back eval cases in parallel. Use when the user says "grade my agent", "make it pass the rubric", "iterate until it's good", "is it good enough", or when the orchestrator routes phase=grade-iterate. outcome_builder.py builds the user.define_outcome payload (rubric required, max_iterations clamped 1..20 — never unbounded); verdict_reader.py reads the grader result and recommends the next move; eval_scaffold.py generates held-back cases + a parallel run plan (capped at the 25-thread CMA ceiling). Distinct from stage-launch (first launch) and run-without-you (scheduling).

Google Workspace CLI operations: setup diagnostics, security audit, recipe discovery, and output analysis. Usage: /google-workspace <setup|audit|recipe|analyze> [options]

Google Workspace administration via the gws CLI (github.com/googleworkspace/cli). Install, authenticate, and automate Gmail, Drive, Sheets, Calendar, Docs, Chat, and Tasks. Run security audits and use local recipe templates and persona bundles. Use for Google Workspace admin, gws CLI setup, Gmail automation, Drive management, or Calendar scheduling.