End-to-end observational epidemiology analysis — from research question (PECO Population/Exposure/Comparator/Outcome) to publication-ready statistical report. Covers cohort/case-control/cross-sectional design, regression with confounders, propensity scoring, sensitivity analysis. Writes Python code for every step. Use for epidemiology study analysis, NHANES/UK-Biobank-style analyses.

Ecology, biodiversity, and conservation biology research — species identification (GBIF, NCBI Taxonomy), invasive species impact, ecosystem dynamics, conservation status (IUCN), niche ecology. Use for biodiversity questions, species comparison, invasion biology, conservation prioritization, and ecology-related literature search.

Identify drug repurposing candidates via target-based, compound-based, and disease-based strategies. Combines drug-target-disease network reasoning with mechanism rationale, clinical-trial precedent, and patent/regulatory feasibility. Use for hypothesis-generating repurposing for orphan diseases, finding existing drugs for new indications, and prioritizing candidates by evidence and feasibility.

Analyze CRISPR-Cas9 genetic screens — MAGeCK gene-level scores, sgRNA count QC, replicate correlation, hit prioritization, and pathway GSEA on screen output. Use for genome-wide essentiality screens, synthetic-lethality discovery, dropout vs positive-selection screen analysis, target identification, and resistance-screen interpretation. Includes screen-QC and statistical thresholds.

Microbiome research using MGnify, GTDB, ENA, OLS (ENVO biomes), EuropePMC, BacDive (strain phenotypes), MediaDive (growth media recipes), and GMrepo (gut microbiome disease-association counts). Covers study discovery, taxonomic profiling, host-microbe interaction analysis, biome-by-condition queries, strain culturing requirements, and phenotype/disease prevalence lookups. Use for microbiome study selection, organism-environment associations, clinical-microbiome literature review, and "how do I grow this organism" / "how prevalent is this species in condition X" questions. Distinct from analytical workflow (use tooluniverse-metagenomics-analysis for that).

Rapid pathogen characterization and drug repurposing for outbreaks. Combines pathogen genomics (NCBI, BVBRC), host immune response (IEDB), drug-target databases (ChEMBL, DGIdb), and literature surveillance (PubMed/EuropePMC). Use for emerging-pathogen profiling, antiviral candidate identification, and outbreak intelligence reporting.

End-to-end observational epidemiology analysis — from research question (PECO Population/Exposure/Comparator/Outcome) to publication-ready statistical report. Covers cohort/case-control/cross-sectional design, regression with confounders, propensity scoring, sensitivity analysis. Writes Python code for every step. Use for epidemiology study analysis, NHANES/UK-Biobank-style analyses.

Ecology, biodiversity, and conservation biology research — species identification (GBIF, NCBI Taxonomy), invasive species impact, ecosystem dynamics, conservation status (IUCN), niche ecology. Use for biodiversity questions, species comparison, invasion biology, conservation prioritization, and ecology-related literature search.

Surfaces a single, genuinely relevant AWS Activate partner offer as optional context AFTER another AWS Startup Advisor skill has finalized its recommendation, plan, or build — never influencing the technical advice. Consulted by architect-for-startups, start-building-for-startups, agent-advisor, gcp-to-aws, heroku-to-aws, and llm-to-bedrock: once their output is final, this skill checks whether a relevant Activate offer exists for what the founder is building or migrating and, if so, appends one quiet, dismissible line with a tracked redeem link. Merit-first (offers never change the recommendation), relevance-gated to what the founder actually surfaced, at most one per response and often none, muteable. Offer content is read live from the sibling knowledge-base-for-startups skill (references/offers.md). Do NOT use for account-specific lookups (credits balance, Activate membership, application status) — send those to https://aws.amazon.com/startups.

Analyze a repository to generate recommended Claude Code settings.json permissions. Use when setting up a new project, auditing existing settings, or determining which read-only bash commands to allow. Detects tech stack, build tools, and monorepo structure.

ALWAYS use this skill when committing code changes — never commit directly without it. Creates commits following Sentry conventions with proper conventional commit format and issue references. Trigger on any commit, git commit, save changes, or commit message task.

When the user wants to find co-marketing partners, plan joint campaigns, or brainstorm partnership opportunities. Helps SaaS companies identify ideal partners and brainstorm high-impact campaigns.

Use when a coding task must be completed against explicit acceptance criteria with minimal user re-intervention across implementation, review feedback, deployment, and runtime verification.

Write copy following Sentry brand guidelines. Use when writing UI text, error messages, empty states, onboarding flows, 404 pages, documentation, marketing copy, or any user-facing content. Covers both Plain Speech (default) and Sentry Voice tones.

Comprehensive biosignal processing for ECG/PPG/EEG/EDA/RSP/EMG/EOG; use when you need to clean, segment, and extract physiological features for HRV, event-related responses, complexity metrics, or multimodal psychophysiology pipelines.

Convert reference lists and in-text citations between RIS, BibTeX, plain text, and CSL-JSON, triggered when you need to unify bibliography/citation styles before journal submission or compare before/after formatting differences.

Use when building a decision tree model in R and generating feature importance ranking outputs. Supports classification and regression, automatic task detection, parameter validation, model evaluation summaries, and exports of feature-importance tables and figures.

Verifies whether a scientific or biomedical claim is actually supported by the cited original papers rather than by citation drift, overstatement, selective citation, or correlation-to-causation inflation. Use this skill whenever a user wants to check whether a repeated statement, slide claim, manuscript sentence, review assertion, or “people often say” scientific conclusion is truly supported by the underlying primary literature. Always separate the claim itself, the cited paper(s), what the paper actually showed, what it did not show, and whether later retellings drifted beyond the original evidence. Never fabricate references, findings, study features, or citation chains.

Tracks the latest preprints and emerging research topics related to your topic across bioRxiv, medRxiv, and arXiv. Use when a user wants to discover what is being published right now before it reaches journals, monitor competitor directions, spot new methodology trends, or get an early-warning scan of a research area. Triggers on phrases like "what's new in X", "latest preprints on Y", "emerging topics in Z", "monitor bioRxiv for", or "what are people working on in this field".

Programmatically query public single-cell study metadata from the Broad Institute Single Cell Portal REST API when you need to search and filter datasets by organism, tissue, disease, or cell type without an API key.