Vibe-Skills

Structured hypothesis formulation from observations. Use when you have experimental observations or data and need to formulate testable hypotheses with predictions, propose mechanisms, and design experiments to test them. Also owns explicit HypoGeniC-style or automated LLM-driven hypothesis generation/testing requests inside this single skill. For open-ended ideation use scientific-brainstorming.

Property-based testing with Hypothesis for discovering edge cases and validating invariants. Use when implementing comprehensive test coverage, testing complex logic with many inputs, or validating mathematical properties and invariants across input domains. Triggered by: hypothesis, property-based testing, @given, strategies, generative testing.

Use when the user asks to generate or edit images via the OpenAI Image API (for example: generate image, edit/inpaint/mask, background removal or replacement, transparent background, product shots, concept art, covers, or batch variants); run the bundled CLI (`scripts/image_gen.py`) and require `OPENAI_API_KEY` for live calls.

Query and download public cancer imaging data from NCI Imaging Data Commons using idc-index. Use for accessing large-scale radiology (CT, MR, PET) and pathology datasets for AI training or research. No authentication required. Query by metadata, visualize in browser, check licenses.

Create professional infographics using Nano Banana Pro AI with smart iterative refinement. Uses Gemini 3 Pro for quality review. Integrates research-lookup and web search for accurate data. Supports 10 infographic types, 8 industry styles, and colorblind-safe palettes.

Comprehensive toolkit for preparing ISO 13485 certification documentation for medical device Quality Management Systems. Use when users need help with ISO 13485 QMS documentation, including (1) conducting gap analysis of existing documentation, (2) creating Quality Manuals, (3) developing required procedures and work instructions, (4) preparing Medical Device Files, (5) understanding ISO 13485 requirements, or (6) identifying missing documentation for medical device certification. Also use when users mention medical device regulations, QMS certification, FDA QMSR, EU MDR, or need help with quality system documentation.

Use when the user asks to create, scaffold, or edit Jupyter notebooks (`.ipynb`) for experiments, explorations, or tutorials; prefer the bundled templates and run the helper script `new_notebook.py` to generate a clean starting notebook.

AI工作经验知识库管理。适用于用户明确要求'保存到Obsidian'、'记录这个'、'save this insight'、'memo this'、'capture this'等知识沉淀场景。将对话中的提示词、模式、问题修复、想法和效率优化保存到Obsidian知识库，并自动同步到GitHub。

This skill should be used when working with LaminDB, an open-source data framework for biology that makes data queryable, traceable, reproducible, and FAIR. Use when managing biological datasets (scRNA-seq, spatial, flow cytometry, etc.), tracking computational workflows, curating and validating data with biological ontologies, building data lakehouses, or ensuring data lineage and reproducibility in biological research. Covers data management, annotation, ontologies (genes, cell types, diseases, tissues), schema validation, integrations with workflow managers (Nextflow, Snakemake) and MLOps platforms (W&B, MLflow), and deployment strategies.

Latch platform for bioinformatics workflows. Build pipelines with Latch SDK, @workflow/@task decorators, deploy serverless workflows, LatchFile/LatchDir, Nextflow/Snakemake integration.

Use when creating or revising LaTeX research posters with beamerposter, tikzposter, or baposter, including poster layout, typography, color, print sizing, figure placement, QR codes, compilation, and print-ready PDF checks.

Use when building a LaTeX manuscript submission pipeline with templates, latexmk, BibTeX/Biber, chktex, latexindent, CI PDF builds, compile debugging, and submission zip packaging.

Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting systematic literature reviews, meta-analyses, research synthesis, or comprehensive literature searches across biomedical, scientific, and technical domains. Creates professionally formatted markdown documents and PDFs with verified citations in multiple citation styles (APA, Nature, Vancouver, etc.).

Codex-local role pack for dialectic multi-agent reviews, designed to be compatible with the local vibe skill.

LQF Machine Learning Expert Guide - Routed skill for ML/Statistical Modeling with Critical Discussion Mode. Triggers on: machine learning, modeling, prediction, training, classification, regression, clustering, deep learning, neural network, model evaluation, feature engineering, hyperparameter tuning, overfitting, underfitting, baseline, ablation study, critique my approach, review my model, is this a good idea, should I use, what's wrong with, evaluate my solution, challenge my assumptions, discuss my approach Engages in critical discussion with minimum 3 rounds of iterative refinement. Challenges both user proposals and own suggestions with fact-based critique. Demands evidence and baselines before accepting solutions.

Treat manuscripts as software: version control, reproducible builds, figure pipelines, CI, and structured repo layout. Helps teams avoid 'final_v7' chaos and ensures submission-ready artifacts.

Comprehensive markdown and Mermaid diagram writing skill that establishes text-based diagrams as the DEFAULT documentation standard. Use this skill when creating ANY scientific document, report, analysis, or visualization — it ensures all outputs are in version-controlled, token-efficient markdown with embedded Mermaid diagrams as the source of truth, with clear pathways to downstream Python or AI-generated images. Includes full style guides (markdown + mermaid), 24 diagram type references, and 9 document templates ready to use.

Generate comprehensive market research reports and industry/competitive analysis in the style of top consulting firms. Use for market sizing, competitive landscape, market entry, investment thesis, strategic recommendations, and consulting-style business reports. Do not use for scientific reports, paper writing, LaTeX submission/PDF builds, EDGAR/FRED/Treasury/Data Commons data retrieval, or biomedical literature evidence work.

Convert files and office documents to Markdown. Supports PDF, DOCX, PPTX, XLSX, images (with OCR), audio (with transcription), HTML, CSV, JSON, XML, ZIP, YouTube URLs, EPubs and more.

Spectral similarity and compound identification for metabolomics. Use for comparing mass spectra, computing similarity scores (cosine, modified cosine), and identifying unknown compounds from spectral libraries. Best for metabolite identification, spectral matching, library searching. For full LC-MS/MS proteomics pipelines use pyopenms.