tooluniverse-rare-disease-diagnosis
Rare disease differential diagnosis from patient phenotype — HPO term matching to candidate diseases (Orphanet, OMIM), gene panel prioritization, ACMG variant interpretation, and structure-based variant analysis. Use for diagnostic odyssey assistance, phenotype-to-disease ranking, and genetic-counseling differential generation.
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Critical
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Security
1 critical severity finding. Installing this skill is not recommended: please review these findings carefully if you do intend to do so.
E005: Suspicious download URL detected in skill instructions.
What this means
Detected a suspicious URL in the skill instructions that could lead the agent to download and execute malicious scripts or binaries. This includes links to executables from untrusted sources, typosquatting of official packages, URL shorteners that obscure the destination, and personal file hosting services.
Why it was flagged
These URLs point to a direct GitHub VCS install and a non-official vendor/API host used by the skill to distribute/activate a proprietary Python package (ESM) — installing code directly from a specific GitHub commit and registering at a third-party forge are unvetted distribution vectors that can be used to deliver malicious code or credentials.
Low
Low-risk findings.
1 low severity finding. Worth noting, but not necessarily harmful.
W011: Third-party content exposure detected (indirect prompt injection risk).
What this means
The skill exposes the agent to untrusted, user-generated content from public third-party sources, creating a risk of indirect prompt injection. This includes browsing arbitrary URLs, reading social media posts or forum comments, and analyzing content from unknown websites.
Why it was flagged
The required runtime workflow ingests outsider-authored free text from the user’s phenotype/symptom description (e.g., symptoms_list in Phase 1 and symptom_keywords in Phase 2) and feeds it into LLM tool calls like `HPO_search_terms(query=symptom)` and `Orphanet_search_diseases(query=keyword)` before any database item selection.
- Repository
- mims-harvard/ToolUniverse
- Commit
089eb8e
- Audited
- Security analysis
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