Comprehensive immune repertoire analysis for T-cell and B-cell receptor sequencing data. Analyze TCR/BCR repertoires to assess clonality, diversity, V(D)J gene usage, CDR3 characteristics, convergence, and predict epitope specificity. Integrate with single-cell data for clonotype-phenotype associations. Use for adaptive immune response profiling, cancer immunotherapy research, vaccine response assessment, autoimmune disease studies, or repertoire diversity analysis in immunology research.

Discover genes associated with diseases and traits using GWAS data from the GWAS Catalog (500,000+ associations) and Open Targets Genetics (L2G predictions). Identifies genetic risk factors, prioritizes causal genes via locus-to-gene scoring, and assesses druggability. Use when asked to find genes associated with a disease or trait, discover genetic risk factors, translate GWAS signals to gene targets, or answer questions like "What genes are associated with type 2 diabetes?"

Compare GWAS studies, perform meta-analyses, and assess replication across cohorts. Integrates NHGRI-EBI GWAS Catalog and Open Targets Genetics to compare study designs, effect sizes, ancestry diversity, and heterogeneity statistics. Use when comparing GWAS studies for a trait, performing meta-analysis of genetic loci, assessing replication across cohorts, or exploring the genetic architecture of complex diseases.

Transform GWAS signals into actionable drug targets and repurposing opportunities. Performs locus-to-gene mapping, target druggability assessment, existing drug identification, safety profile evaluation, and clinical trial matching. Use when discovering drug targets from GWAS data, finding drug repurposing opportunities from genetic associations, or translating GWAS findings into therapeutic leads.

Perform comprehensive gene enrichment and pathway analysis using gseapy (ORA and GSEA), PANTHER, STRING, Reactome, and 40+ ToolUniverse tools. Supports GO enrichment (BP, MF, CC), KEGG, Reactome, WikiPathways, MSigDB Hallmark, and 220+ Enrichr libraries. Handles multiple ID types (gene symbols, Ensembl, Entrez, UniProt), multiple organisms (human, mouse, rat, fly, worm, yeast), customizable backgrounds, and multiple testing correction (BH, Bonferroni). Use when users ask about gene enrichment, pathway analysis, GO term enrichment, KEGG pathway analysis, GSEA, over-representation analysis, functional annotation, or gene set analysis.

Retrieves gene expression and omics datasets from ArrayExpress and BioStudies with gene disambiguation, experiment quality assessment, and structured reports. Creates comprehensive dataset profiles with metadata, sample information, and download links. Use when users need expression data, omics datasets, or mention ArrayExpress (E-MTAB, E-GEOD) or BioStudies (S-BSST) accessions.

Production-ready genomics and epigenomics data processing for BixBench questions. Handles methylation array analysis (CpG filtering, differential methylation, age-related CpG detection, chromosome-level density), ChIP-seq peak analysis (peak calling, motif enrichment, coverage stats), ATAC-seq chromatin accessibility, multi-omics integration (expression + methylation correlation), and genome-wide statistics. Pure Python computation (pandas, scipy, numpy, pysam, statsmodels) plus ToolUniverse annotation tools (Ensembl, ENCODE, SCREEN, JASPAR, ReMap, RegulomeDB, ChIPAtlas). Supports BED, BigWig, methylation beta-value matrices, Illumina manifest files, and multi-sample clinical data. Use when processing methylation data, ChIP-seq peaks, ATAC-seq signals, or answering questions about CpG sites, differential methylation, chromatin accessibility, histone marks, or epigenomic statistics.

Comprehensive CRISPR screen analysis for functional genomics. Analyze pooled or arrayed CRISPR screens (knockout, activation, interference) to identify essential genes, synthetic lethal interactions, and drug targets. Perform sgRNA count processing, gene-level scoring (MAGeCK, BAGEL), quality control, pathway enrichment, and drug target prioritization. Use for CRISPR screen analysis, gene essentiality studies, synthetic lethality detection, functional genomics, drug target validation, or identifying genetic vulnerabilities.

Genomic file toolkit. Read/write SAM/BAM/CRAM alignments, VCF/BCF variants, FASTA/FASTQ sequences, extract regions, calculate coverage, for NGS data processing pipelines.

Electronic lab notebook API integration. Access notebooks, manage entries/attachments, backup notebooks, integrate with Protocols.io/Jupyter/REDCap, for programmatic ELN workflows.

DNAnexus cloud genomics platform. Build apps/applets, manage data (upload/download), dxpy Python SDK, run workflows, FASTQ/BAM/VCF, for genomics pipeline development and execution.

Use when the user wants to reverse-engineer an existing image ad into a reusable prompt template. Validates via Arcads — picks gpt-image-2 or Nano Banana at Phase 1. Triggers on "clone this ad as a template", "reverse engineer this ad", "turn this ad into a prompt", "extract a template", "make this ad reusable", "add to my prompt library", "study this ad and make a template". Input is an EXISTING ad image; does NOT trigger for fresh generation (use chatgpt-image-ad or nano-banana-image-ad).

Generate high-CTR YouTube thumbnails using Nano Banana 2 via the Arcads external API. Handles reference image upload, character likeness alignment, proven CTR-tested prompt formulas, and parallel batch generation. Use when the user asks to create a YouTube thumbnail, video thumbnail, A/B test thumbnail variations, or refers to thumbnail design with their face, brand assets, or product photos.

Generate one or more standalone Meta image-ad creatives via ChatGPT Image 2 (gpt-image-2) through the Arcads external API. Locks the model, auto-strips platform chrome, enforces edge-safe layouts and glyph-safety inside body text. Use when the user asks for a "gpt-image-2 ad", "ChatGPT Image ad", "Image 2 ad creative", "make a static image ad with GPT", or anchors on a need for typography-heavy / dense-text / UI-mimicry ad creatives (chat threads, comparison tables, fake search results, iOS dialogs, Slack snapshots, ChatGPT-conversation ads, Apple Notes lists). Does NOT trigger on Nano Banana cues — use nano-banana-image-ad for those.

Clone an existing video ad for a different product or offer. Analyzes the source video's style, pacing, camera work, dialogue, and tone, then adapts and generates a new Seedance 2.0 video customized for the user's product. End-to-end workflow: input video → analysis → adapted prompt → generation → delivery. Use when someone says "clone this ad", "make this ad but for my product", "recreate this video for my brand", or provides a video ad and a product image asking for a similar video.

Creates and retrieves AI video and image-related assets via the Arcads external API (Seedance 2.0, Sora 2, Veo 3.1, Kling, Grok Video, Nano Banana, b-roll, scene, script/actor flows). Loads prompts from the bundled prompting guide and model library, respects HTTP Basic auth from ARCADS_API_KEY, and polls assets/videos until ready. Use when the user mentions Arcads, external-api.arcads.ai, Seedance, Sora2, Veo, Kling, Nano Banana, b-roll, UGC scripts, or generating marketing creative through Arcads.

Publish finished creatives as live Meta (Facebook/Instagram) ads via the Meta Marketing API, plus research and ad-copy support. Uploads an image or video, builds a multi-variant TEXT_LIQUIDITY creative, and creates a PAUSED ad in an existing ad set. Also pulls top-performing ads (ranked by ROAS) and competitor ads from the Ad Library to inform copy. Use when the user asks to deploy / publish / launch a creative as a Meta or Facebook ad, build a Meta ad, push a video or image into an ad set, pull their top ads, or research competitor ads. Not for generating creative (use the image/video skills) and not for writing AdTable/Airtable rows (use adtable-light).

Look up Twitter/X profiles - get bio, followers, tweets, and engagement

Search TikTok - find profiles, videos, hashtags, and trending content

Find TikTok influencers using Apify's Influencer Discovery Agent. Use when the user wants to discover TikTok creators or influencers in any niche.