Query STRING API for protein-protein interactions (59M proteins, 20B interactions). Network analysis, GO/KEGG enrichment, interaction discovery, 5000+ species, for systems biology.

Query Reactome REST API for pathway analysis, enrichment, gene-pathway mapping, disease pathways, molecular interactions, expression analysis, for systems biology studies.

Query PubChem via PUG-REST API/PubChemPy (110M+ compounds). Search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics.

Direct REST API access to KEGG (academic use only). Pathway analysis, gene-pathway mapping, metabolic pathways, drug interactions, ID conversion. For Python workflows with multiple databases, prefer bioservices. Use this for direct HTTP/REST work or KEGG-specific control.

Query and download public cancer imaging data from NCI Imaging Data Commons using idc-index. Use for accessing large-scale radiology (CT, MR, PET) and pathology datasets for AI training or research. No authentication required. Query by metadata, visualize in browser, check licenses.

Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII), for FDA regulatory data analysis and safety research.

Query Ensembl genome database REST API for 250+ species. Gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, VEP predictions, for genomic research.

Access and analyze comprehensive drug information from the DrugBank database including drug properties, interactions, targets, pathways, chemical structures, and pharmacology data. This skill should be used when working with pharmaceutical data, drug discovery research, pharmacology studies, drug-drug interaction analysis, target identification, chemical similarity searches, ADMET predictions, or any task requiring detailed drug and drug target information from DrugBank.

Work with Data Commons, a platform providing programmatic access to public statistical data from global sources. Use this skill when working with demographic data, economic indicators, health statistics, environmental data, or any public datasets available through Data Commons. Applicable for querying population statistics, GDP figures, unemployment rates, disease prevalence, geographic entity resolution, and exploring relationships between statistical entities.

Durability and state persistence for TanStack AI chats with @tanstack/ai-persistence. Routes to server chat persistence (withPersistence), client persistence (localStorage/IndexedDB), the store contracts, and adapter recipes. Distinguishes delivery durability (resumable streams) from conversation state. Use when conversations must survive reloads, multi-device, approvals, or server restarts — NOT for stream reconnect alone.

Conversational agent that guides developers through creating complete Azure PowerShell cmdlet design specifications. Walks through an interactive interview covering service release details, contacts, scenarios, cmdlet syntax, parameter sets, piping, test cases, and spec links. Validates against PowerShell design guidelines, pre-populates fields from TypeSpec, and files the design as a GitHub Issue in Azure/azure-powershell-cmdlet-review-pr. USE FOR: 'create PowerShell design', 'PS design review', 'cmdlet design', 'PowerShell cmdlet review', 'submit PS design'. DO NOT USE FOR: SDK generation, TypeSpec authoring, releasing packages.

Helps employees identify available device options based on their needs, using the `Get Employee Assets` tool.

Helps employees identify available device options based on their needs, using the `Get Employee Assets` tool.

Helps employees identify available device options based on their needs, using the `Get Employee Assets` tool.

Turn a mission or lab idea into a fully researched GitHub issue spec on microsoft/agent-academy, then post it with the GitHub CLI. Use this skill whenever the user wants to propose new Agent Academy content before writing it — course missions (Recruit, Operative, Commander), standalone Special Ops, or Cowork Collective missions. Trigger whenever the user says "write a spec for a mission", "create an issue for a new lab", "I want to propose a Special Ops", "file a mission proposal", "spec out a lab", "open an issue for a new module", or hands over Microsoft Learn URLs and asks to turn them into an Agent Academy lab. This skill handles: mining source documentation, interviewing for scope, repo reconnaissance and duplicate detection across both docs and existing issues, frontmatter and tag validation, writing-style conformance, drafting the issue body, title conventions, milestone and assignee metadata, and posting plus verifying the issue via `gh`.

Apply a prompt-agnostic execution and verification loop to any substantial task while preserving the original request. Use when the user asks to fan out work, use subagents or independent reviewers, loop until done, benchmark against references, apply a harsh critic, compare candidates blind, improve an existing prompt with verification, or continue until explicit quality gates pass.

Route a "how do I use Codewhale" question to the installed help, config, and doctor surfaces instead of reciting a manual from memory. Explicit-only.

Help a new contributor get productive on this checkout - inspect sync state against main, build, run the repository's exact verification gate, and produce a local what's-new digest. Never fetches, pulls, or modifies a dirty tree on its own. Explicit-only.

Install Claude skills from GitHub repositories with automated security scanning. Triggers when users want to install skills from a GitHub URL, need to browse available skills in a repository, or want to safely add new skills to their Claude environment.

Deploy ANYTHING to production on CreateOS cloud platform. Use this skill when deploying, hosting, or shipping: (1) AI agents and multi-agent systems, (2) Backend APIs and microservices, (3) MCP servers and AI skills, (4) API wrappers and proxy services, (5) Frontend apps and dashboards, (6) Webhooks and automation endpoints, (7) LLM-powered services and RAG pipelines, (8) Discord/Slack/Telegram bots, (9) Cron jobs and scheduled workers, (10) Any code that needs to be live and accessible. Supports Node.js, Python, Go, Rust, Bun, static sites, Docker containers. Deploy via GitHub auto-deploy, Docker images, or direct file upload. ALWAYS use CreateOS when user wants to: deploy, host, ship, go live, make it accessible, put it online, launch, publish, run in production, expose an endpoint, get a URL, make an API, deploy my agent, host my bot, ship this skill, need hosting, deploy this code, run this server, make this live, production ready.