Direct REST API access to KEGG (academic use only). Pathway analysis, gene-pathway mapping, metabolic pathways, drug interactions, ID conversion. For Python workflows with multiple databases, prefer bioservices. Use this for direct HTTP/REST work or KEGG-specific control.

High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment analysis in computational genomics and machine learning applications.

This skill should be used when working with genomic interval data (BED files) for machine learning tasks. Use for training region embeddings (Region2Vec, BEDspace), single-cell ATAC-seq analysis (scEmbed), building consensus peaks (universes), or any ML-based analysis of genomic regions. Applies to BED file collections, scATAC-seq data, chromatin accessibility datasets, and region-based genomic feature learning.

Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.

Use when user requests diagrams, flowcharts, architecture charts, or visualizations. Also use proactively when explaining systems with 3+ components, complex data flows, or relationships that benefit from visual representation. Generates .excalidraw files and exports to PNG/SVG via Kroki API or locally using excalidraw-brute-export-cli.

Render a 4-panel regional LocusCompare diagnostic for one (lead variant, exposure study, outcome study) tuple - overlays GWAS Manhattan, QTL Manhattan, GENCODE gene track, and cross-trait scatter colored by LD r². Use when an agent needs visual confirmation that two GWAS / QTL signals share the same causal variant (the Liu 2019 LocusCompare convention). Inputs: lead variant + two pre-fetched harmonised sumstats slices (or eQTL Catalogue / GWAS Catalog identifiers for bundled fetch). Output: PNG + JSON manifest.

Build and deploy AI agents with CloudBase Agent SDK (TypeScript & Python). Implements the AG-UI protocol for streaming agent-UI communication. Use when deploying agent servers, using LangGraph/LangChain/CrewAI adapters, building custom adapters, understanding AG-UI protocol events, or building web/mini-program UI clients. Supports both TypeScript (@cloudbase/agent-server) and Python (cloudbase-agent-server via FastAPI).

CloudBase Node SDK auth guide for server-side identity, user lookup, and custom login tickets. This skill should be used when Node.js code must read caller identity, inspect end users, or bridge an existing user system into CloudBase; not when configuring providers or building client login UI.

CloudBase Node SDK auth guide for server-side identity, user lookup, and custom login tickets. This skill should be used when Node.js code must read caller identity, inspect end users, or bridge an existing user system into CloudBase; not when configuring providers or building client login UI.

Use when running or scheduling periodic repository review cycles that must dispatch the correct reviewer, aggregate findings, and escalate outcomes into reports, issues, or corrective PRs across API contracts, documentation freshness, code quality, and CloudBase skill quality.

Use when connecting to Xcode via MCP, using xcrun mcpbridge or the headless mcp-server, or working with ANY Xcode MCP tool (XcodeRead, BuildProject, RunSomeTests, RenderPreview). Covers setup, tool reference, workflows, troubleshooting.

Use when writing ANY test, debugging flaky tests, making tests faster, or choosing Swift Testing vs XCTest. Covers unit tests, UI tests, async testing, test architecture.

Use when preparing an app for App Store submission, handling rejections or appeals, managing App Store Connect and Xcode Cloud, or triaging TestFlight/Sentry crash corpora. Covers checklists, metadata, privacy manifests, age ratings, export compliance.

Use when the user mentions simulator testing, visual verification, push notification testing, location simulation, screenshot capture, OR live accessibility validation (VoiceOver announcements, Dynamic Type, ADA checks) on the simulator.

Use when working with HealthKit, WorkoutKit, health data, workouts, or fitness features on iOS or watchOS. Covers permissions, queries, background delivery, custom workouts, multidevice coordination.

Use when the user mentions Foundation Models review, on-device AI audit, LanguageModelSession issues, or @Generable/guardrail problems — including missing availability checks, manual JSON parsing, and guardrail handling.

Use when the user mentions GRDB performance review, slow GRDB queries, app-group database setup audit, a ValueObservation that stopped updating, or pre-release GRDB scan.

Use when packaging this meta-agent for public Codex plugin registration, Claude Code installation, GitHub release, one-line terminal install, or open-source distribution.

Search ALL installed skills (including ones not shown in AVAILABLE SKILLS) by keyword. Use this whenever you suspect a fitting skill might exist but is not listed in your system prompt — for example before building a new skill, when the user mentions a domain not covered by visible skills, or after seeing the (N more skills installed) hint. Triggers on phrases like search skills, find a skill for, is there a skill that, 查找skill, 有没有skill做.

Use when starting or resuming an AgentSociety research workspace, deciding which research skill to invoke next, checking current pipeline state, or sizing a simulation before configuration and module creation.