feynman

Register or audit Feynman-managed model endpoints. Use when a research workflow needs a local or remote model service, endpoint health checks, credential refs, startup scripts, or inference routing.

Run a literature review using paper search and primary-source synthesis. Use when the user asks for a lit review, paper survey, state of the art, or academic landscape summary on a research topic.

Design protein sequences around ligand or small-molecule contexts with LigandMPNN-style workflows. Use when a task asks for ligand-aware protein design, residue redesign, constraints, or design ranking.

Inspect visible research run state, scheduled research follow-ups when available, and durable watch artifacts. Use when the user asks what's running for a research workflow or wants research-run status.

Build a source-backed biomedical indication dossier. Use when a research task asks for disease biology, target rationale, patient segmentation, biomarkers, trials, drugs, competitive landscape, or translational evidence.

Apply scientific plotting and figure-quality rules to a single plot or panel. Use when drawing, cleaning, labeling, or reviewing plots for research artifacts.

Compose a publication-grade multi-panel scientific figure from a claim, dataset, or draft result. Use when the task needs panel planning, consistent figure layout, figure review, or final figure assembly.

Use ESM2 protein language models for embeddings, mutation scoring, remote homology, or representation analysis. Use when a task needs protein embeddings, zero-shot variant scores, clustering, or sequence-function triage.

Use Evo2-style biological sequence models for generation, scoring, or variant-effect analysis. Use when a task asks about DNA/RNA/protein sequence likelihood, editing, design, or long-context biological modeling.

Predict quick protein structures with ESMFold-style workflows. Use when a task needs fast MSA-free folding, sequence triage, variant structure screening, or confidence review.

Explain research, papers, or technical ideas in plain English with minimal jargon, concrete analogies, and clear takeaways. Use when the user says "ELI5 this", asks for a simple explanation of a paper or research result, wants jargon removed, or asks what something technically dense actually means.

Execute research code inside isolated Docker containers for safe replication, experiments, and benchmarks. Use when the user selects Docker as the execution environment or asks to run code safely, in isolation, or in a sandbox.

Run or plan DiffDock molecular docking workflows. Use when a task asks for protein-ligand pose prediction, docking setup, ligand/protein preparation, pose ranking, or docking-result verification.

Run a thorough, source-heavy investigation on any topic. Use when the user asks for deep research, a comprehensive analysis, an in-depth report, or a multi-source investigation. Produces a cited research brief with provenance tracking.

Configure Feynman specialists, skills, connectors, permissions, memory categories, compute providers, and project setup. Use when the task asks to customize the research workbench or create a reusable Feynman research capability.

Contribute changes to the Feynman repository itself. Use when the task is to add features, fix bugs, update prompts or skills, change install or release behavior, improve docs, or prepare a focused PR against this repo.

Set up a reproducible Feynman compute environment for research jobs. Use when a task needs Python/R packages, GPU libraries, containers, Modal, SSH, caches, or managed model runtime setup.

Run or prepare Chai-1 structure predictions for biomolecular complexes. Use when a task asks for Chai-1 inputs, multimers, ligand/nucleic acid structure prediction, or confidence review.

Use Borzoi-style regulatory genomics models for sequence-to-expression or variant-effect analysis. Use when the task asks for noncoding variant impact, regulatory sequence design, or expression prediction.

Run or plan Boltz biomolecular structure predictions for proteins, complexes, ligands, or nucleic-acid assemblies. Use when a task asks for Boltz setup, inputs, outputs, confidence interpretation, or reproduction.

Bounded research experiment loop that tries hypotheses, measures benchmark evidence, keeps what works, and records what fails. Use when the user asks to optimize a research metric, run an experiment loop, improve model/retrieval/evaluation performance iteratively, or benchmark a research hypothesis.

Predict or audit protein structures with AlphaFold2-style workflows. Use when a research task needs monomer/multimer structure prediction, MSA/template handling, confidence metrics, or comparison against PDB/AlphaFold references.

Search, read, and query research papers via Feynman's alphaXiv-backed alpha tools. Use when the user asks about academic papers, wants to find research on a topic, needs to read a specific paper, ask questions about a paper, inspect a paper's code repository, or manage paper annotations.